CAB39L and SCML2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAB39L	SCML2
Description		calcium binding protein 39 like	Scm polycomb group protein like 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Serine/threonine Protein Kinase Complex	Nucleus PcG Protein Complex
	Molecular Function	Protein Binding Protein Serine/threonine Kinase Activator Activity	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Intracellular Signal Transduction	Regulation Of DNA-templated Transcription Anatomical Structure Morphogenesis Negative Regulation Of DNA-templated Transcription
Pathways		Energy dependent regulation of mTOR by LKB1-AMPK
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Heel bone mineral density x serum urate levels interaction ( 34046847) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) PR interval ( 32439900)
Interacting Genes		4 interacting genes: CFTR MLH1 MX1 SCML2	8 interacting genes: CAB39L CDKN1A LNX1 NCK2 RNF4 SFMBT2 SRGAP2B USP7
Entrez ID		81617	10389
HPRD ID		12993	02195
Ensembl ID		ENSG00000102547	ENSG00000102098
Uniprot IDs		Q86WE6 Q9H9S4	Q9UQR0
PDB IDs		3ZHP	1OI1 2BIV 2MEM 2VYT 4EDU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Male Meiosis Chromosome Segregation MutLalpha Complex Chiasma Nuclear-transcribed MRNA Catabolic Process Late Recombination Nodule MRNA Catabolic Process Meiotic Metaphase I Homologous Chromosome Alignment U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Isotype Switching To IgA Isotypes RNA Catabolic Process Guanine/thymine Mispair Binding MutSalpha Complex Binding Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Regulation Of Mitotic Recombination Meiotic Telomere Clustering Mismatch Repair Complex Negative Regulation Of Mitotic Recombination Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Interleukin-27-mediated Signaling Pathway Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance U4 SnRNA 3'-end Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process Amelogenesis Telomere Localization ATPase-coupled Inorganic Anion Transmembrane Transporter Activity RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) Mismatched DNA Binding	Nuclear Body
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