TARS2 and ZNF687

		TARS2	ZNF687
Description		threonyl-tRNA synthetase 2, mitochondrial	zinc finger protein 687
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Aminoacyl-tRNA Deacylase Activity Aminoacyl-tRNA Ligase Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity Protein Homodimerization Activity	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Threonyl-tRNA Aminoacylation TRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Regulation Of DNA-templated Transcription
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Threonine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 27494321 30696823) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Body mass index ( 26426971)
Interacting Genes		9 interacting genes: ARL6IP1 ASB6 FKBP7 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFRSF10D	2 interacting genes: CDKN2A TSPYL2
Entrez ID		80222	57592
HPRD ID		18148	13859
Ensembl ID		ENSG00000143374	ENSG00000143373
Uniprot IDs		Q9BW92 U3KQG0	Q8N1G0
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Negative Regulation Of Cell-matrix Adhesion Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Negative Regulation Of Cell-substrate Adhesion Protein Destabilization Cellular Response To Hydrogen Peroxide Regulation Of Mitochondrial Membrane Potential Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Regulation Of Protein Modification Process Response To Hydrogen Peroxide Positive Regulation Of Protein Localization To Nucleus Ligase Inhibitor Activity Cellular Response To Reactive Oxygen Species Mitochondrial Threonyl-tRNA Aminoacylation Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Cell-matrix Adhesion Negative Regulation Of DNA Metabolic Process Regulation Of Protein Localization To Nucleus Response To Reactive Oxygen Species Negative Regulation Of Cell Growth Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Threonine-tRNA Ligase Activity Threonyl-tRNA Aminoacylation Negative Regulation Of Leukocyte Activation Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Negative Regulation Of Growth Cellular Response To Oxidative Stress Regulation Of Cell-substrate Adhesion Senescence-associated Heterochromatin Focus Negative Regulation Of Cell Activation Cellular Response To Progesterone Stimulus Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Immature T Cell Proliferation In Thymus Connexin Binding Mitochondrial Depolarization Oncogene-induced Cell Senescence Cellular Response To Chemical Stress Negative Regulation Of Immature T Cell Proliferation Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of Intracellular Transport Negative Regulation Of Neutrophil Activation Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Dephosphorylation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?