USB1 and RNU6-1

Number of citations of the paper that reports this interaction (PMID 23022480)
5

Data Source:
BioGRID (enzymatic study)

		USB1	RNU6-1
Gene Name		U6 snRNA biogenesis 1	RNA, U6 small nuclear 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	3'-5'-exoribonuclease Activity
	Biological Process	MRNA Processing RNA Splicing U6 SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS			Cognitive performance ( 20125193)
Protein-Protein Interactions		2 interactors: RNU6-1 SMAD4	3 interactors: RBM22 SND1 USB1
Entrez ID		79650	26827
HPRD ID		07815
Ensembl ID		ENSG00000103005	ENSG00000206625
Uniprot IDs		H3BNM8 Q9BQ65
PDB IDs		4H7W
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Nephrogenic Mesenchyme Morphogenesis Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Endocardial Cell Differentiation Formation Of Anatomical Boundary Endothelial Cell Activation Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Brainstem Development SMAD Protein Complex Assembly Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Canal Development Regulation Of Hair Follicle Development Metanephric Mesenchyme Development Heart Valve Formation Endocardial Cushion Formation Endocardium Development Atrioventricular Valve Morphogenesis Regulation Of Hair Cycle Endocardial Cushion Morphogenesis Atrioventricular Valve Development Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Heart Morphogenesis Positive Regulation Of Epithelial To Mesenchymal Transition Heart Valve Morphogenesis Heart Valve Development Endocardial Cushion Development Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Embryonic Axis Specification Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Epithelial To Mesenchymal Transition Gastrulation With Mouth Forming Second Regulation Of Epithelial To Mesenchymal Transition SMAD Protein Signal Transduction Branching Involved In Ureteric Bud Morphogenesis Regulation Of Epidermis Development Ureteric Bud Morphogenesis Anterior/posterior Axis Specification Somatic Stem Cell Maintenance Endothelial Cell Differentiation Neuron Fate Commitment	U6 SnRNA 3'-end Processing Nucleic Acid Phosphodiester Bond Hydrolysis RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Cis Splicing, Via Spliceosome RNA Metabolic Process Gene Expression SnRNA Processing Protein Import Into Nucleus, Translocation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Positive Regulation Of RNA Splicing SnRNA Metabolic Process Cellular Response To Drug Nucleobase-containing Compound Metabolic Process Gene Silencing By RNA Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process
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