HAUS3 and GNG13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAUS3	GNG13
Description		HAUS augmin like complex subunit 3	G protein subunit gamma 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Ciliary Basal Body Intercellular Bridge HAUS Complex Mitotic Spindle Mitotic Spindle Microtubule	Heterotrimeric G-protein Complex Plasma Membrane Membrane Dendrite Synapse
	Molecular Function	Protein Binding	Protein Binding G-protein Beta-subunit Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Microtubule Organizing Center Organization Spindle Assembly Cell Division	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Taste
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Olfactory Signaling Pathway Olfactory Signaling Pathway Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production Sensory perception of sweet, bitter, and umami (glutamate) taste Sensory perception of sweet, bitter, and umami (glutamate) taste High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: ANKRD11 BRME1 CIAO1 GNG13 KDM1A RCOR3 TXLNA TXLNB	39 interacting genes: ABI3 ADAMTSL4 BEX5 CCHCR1 CTAG1A CTAG1B CYSRT1 DISC1 DLG1 DLG4 EMILIN1 FTO GLRX3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 HAUS3 HOXA10 KRT27 KRT34 KRT37 KRT38 KRTAP9-2 LIN7B MEOX2 PAX5 PLSCR2 RASSF10 RPRM RSPO4 TEAD2 TEPSIN TRIM54 UQCC2 VPS16 WASHC3
Entrez ID		79441	51764
HPRD ID		10784	12116
Ensembl ID		ENSG00000214367	ENSG00000127588
Uniprot IDs		Q68CZ6	Q9P2W3
PDB IDs		6PTB 6PTE 7SQK
Enriched GO Terms of Interacting Partners?			Heterotrimeric G-protein Complex Signaling Receptor Complex Adaptor Activity Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament MPP7-DLG1-LIN7 Complex Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Morphogenesis Of An Epithelium GTPase Binding Supramolecular Fiber Organization Protein-containing Complex Binding Presynapse Postsynaptic Density Cytoskeleton Organization Anatomical Structure Morphogenesis Tissue Morphogenesis Developmental Process Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane GTPase Activity Structural Molecule Activity
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