ZNF213 and EEF2KMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF213	EEF2KMT
Description		zinc finger protein 213	eukaryotic elongation factor 2 lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Peptidyl-lysine Trimethylation Methylation
Pathways		Generic Transcription Pathway	Protein methylation
Drugs
Diseases
GWAS		Metabolite levels (X-11787) ( 23934736)
Interacting Genes		8 interacting genes: CFTR EEF2KMT FBXO17 LMO4 LNX1 PPL SCAND1 UBC	12 interacting genes: HPRT1 IFT88 KIAA1328 LNX1 NR0B1 PICK1 PRKAR1B PRTFDC1 TRIP13 ZNF213 ZNF35 ZNF620
Entrez ID		7760	196483
HPRD ID		12224	18018
Ensembl ID		ENSG00000085644	ENSG00000118894
Uniprot IDs		A0A0S2Z4L6 O14771	K7ES84 Q96G04
PDB IDs			8FZB
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport PDZ Domain Binding Modification-dependent Protein Catabolic Process Ventral Spinal Cord Interneuron Differentiation	Guanine Salvage Hypoxanthine Phosphoribosyltransferase Activity GMP Catabolic Process Guanine Metabolic Process Purine Ribonucleoside Salvage Purine Nucleobase Biosynthetic Process Nucleoside Salvage Purine Nucleoside Monophosphate Catabolic Process Purine Nucleobase Metabolic Process Purine Nucleoside Metabolic Process GMP Metabolic Process Purine-containing Compound Salvage Nucleoside Metabolic Process Hippocampal Mossy Fiber To CA3 Synapse Ciliary Base DNA Hairpin Binding Guanine Phosphoribosyltransferase Activity Nucleoside Monophosphate Metabolic Process Purine Ribonucleotide Catabolic Process Hypoxanthine Salvage Purine Nucleotide Catabolic Process Adenine Metabolic Process Hypoxanthine Biosynthetic Process Meiotic Recombination Checkpoint Signaling Nucleotide Catabolic Process AF-2 Domain Binding Hypoxanthine Metabolic Process Response To Silicon Dioxide Membrane Curvature Sensor Activity GMP Salvage Nucleoside Phosphate Catabolic Process IMP Salvage Centriolar Satellite Male Gamete Generation Spermatogenesis Positive Regulation Of Dopamine Metabolic Process AMP Salvage Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation CAMP-dependent Protein Kinase Regulator Activity Female Meiosis I Gamete Generation Metal Ion Binding Positive Regulation Of Fear Response Meiotic Cell Cycle Checkpoint Signaling Negative Regulation Of Actin Nucleation
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