UQCRH and ENTREP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		UQCRH	ENTREP3
Description		ubiquinol-cytochrome c reductase hinge protein	endosomal transmembrane epsin interactor 3
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex III Respiratory Chain Complex	Membrane
	Molecular Function	Protein Binding Quinol-cytochrome-c Reductase Activity	Protein Binding WW Domain Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Cellular Respiration Proton Transmembrane Transport
Pathways		Respiratory electron transport Complex III assembly Complex III assembly
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: ARL8A ENTREP3 NDFIP1 NDFIP2 NPM1 PRRG1 RNF24	3 interacting genes: SNTA1 UQCRH YAP1
Entrez ID		7388	10712
HPRD ID		15629	08511
Ensembl ID		ENSG00000173660	ENSG00000160767
Uniprot IDs		P07919 Q567R0	P81408 Q9Y6J7
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		WW Domain Binding Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Regulation Of Post-translational Protein Modification Regulation Of MRNA Stability Involved In Cellular Response To UV Regulation Of EIF2 Alpha Phosphorylation By DsRNA Positive Regulation Of Protein Modification Process Intracellular Transport Regulation Of Endoribonuclease Activity Negative Regulation Of Protein Transport Negative Regulation Of Isotype Switching To IgE Isotypes Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Regulation Of Ribonuclease Activity Cellular Localization Regulation Of Protein Modification Process Positive Regulation Of Centrosome Duplication Establishment Of Localization In Cell Membrane Golgi Membrane Negative Regulation Of Establishment Of Protein Localization Vacuolar Transport Negative Regulation Of Isotype Switching Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Protein Localization To Nucleolus Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Granular Component Endosome Negative Regulation Of Interleukin-4 Production Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Canonical NF-kappaB Signal Transduction CD4-positive, Alpha-beta T Cell Proliferation Tat Protein Binding Regulation Of Protein Localization To Nucleolus Regulation Of Protein Localization Ribosomal Subunit Export From Nucleus Negative Regulation Of Centrosome Duplication Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of Immunoglobulin Production Spindle Pole Centrosome Ribosomal Large Subunit Binding Endosome Membrane Alpha-beta T Cell Proliferation Regulation Of Isotype Switching To IgG Isotypes Negative Regulation Of Type 2 Immune Response	Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Dystrophin-associated Glycoprotein Complex Syntrophin Complex Anchoring Junction Ventricular Cardiac Muscle Cell Action Potential Nitric-oxide Synthase Binding Generation Of Precursor Metabolites And Energy Respiratory Chain Complex III Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Quinol-cytochrome-c Reductase Activity Respiratory Chain Complex Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Branch Elongation Of An Epithelium Lateral Mesoderm Development Positive Regulation Of Cardiac Muscle Cell Proliferation Cellular Response To Gamma Radiation Intestinal Epithelial Cell Development Bud Elongation Involved In Lung Branching Glandular Epithelial Cell Differentiation Lung Epithelial Cell Differentiation Regulation Of Nephron Tubule Epithelial Cell Differentiation TEAD-YAP Complex Hippo Signaling Notochord Development Negative Regulation Of Stem Cell Differentiation Glycolytic Process Through Fructose-6-phosphate Glucose Catabolic Process Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Female Germ Cell Nucleus Polarized Epithelial Cell Differentiation Trophectodermal Cell Differentiation Glycolytic Process Through Glucose-6-phosphate Cardiac Muscle Tissue Regeneration Enterocyte Differentiation Paraxial Mesoderm Development Intestinal Epithelial Cell Differentiation Lung Cell Differentiation Columnar/cuboidal Epithelial Cell Development Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Cilium Assembly Axis Elongation Proline-rich Region Binding Interleukin-6-mediated Signaling Pathway Canonical Glycolysis Blastocyst Development Sodium Channel Regulator Activity Heart Process Response To Progesterone Cardiac Muscle Cell Action Potential Involved In Contraction
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