TCF20 and TST

Data Source: HiPPIP (Novel)

		TCF20	TST
Name		transcription factor 20	thiosulfate sulfurtransferase
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Extracellular Space Mitochondrion Mitochondrial Matrix
	Molecular Function	DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Binding Thiosulfate-cyanide Sulfurtransferase Activity 5S RRNA Binding Transferase Activity Sulfurtransferase Activity 3-mercaptopyruvate Sulfurtransferase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Sulfur Amino Acid Catabolic Process Cyanate Catabolic Process Epithelial Cell Differentiation RRNA Import Into Mitochondrion RRNA Transport
Pathways		None	Sulfide oxidation to sulfate Degradation of cysteine and homocysteine
Drugs		None	S-Mercaptocysteine
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 ) Antisaccade task score ( 31596458 ) Arterial stiffness ( 31070453 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Body mass index ( 29273807 ) Chronotype ( 30696823 ) Cognitive function ( 25644384 ) Intelligence ( 28530673 ) Isthmus-cingulate cortex volume ( 31530798 ) Refractive error ( 32231278 ) Schizophrenia ( 25056061 29483656 30285260 )	Crohn's disease ( 26192919 ) Inflammatory bowel disease ( 26192919 )
Novel Interactors		6 novel interactors: FBLN1 TBC1D22A TRAM1 TST UGT2B4 ZMYND11	2 novel interactors: CACNA1I TCF20
Interacting Genes		8 interacting genes: AR ESR1 H2AC20 JUN MAPK14 RNF10 RNF4 SMAD1	2 interacting genes: MT-ND1 PRSS1
Entrez ID		6942	7263
HPRD ID		04378	01583
Ensembl ID		ENSG00000100207	ENSG00000128311
Uniprot IDs		Q9UGU0 W5ZR30	A0A384NKQ2 Q16762
PDB IDs		Not available	8AGF
GO Terms Enriched among Interactors		Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Positive Regulation Of Fibroblast Proliferation Positive Regulation Of MiRNA Metabolic Process Estrogen Response Element Binding Prostate Gland Growth Positive Regulation Of Transcription By RNA Polymerase II MAPK Cascade Regulation Of Fibroblast Proliferation Cellular Response To Estrogen Stimulus Mammary Gland Alveolus Development DNA Binding Transcription By RNA Polymerase II Stem Cell Differentiation Positive Regulation Of RNA Biosynthetic Process Prostate Gland Epithelium Morphogenesis Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Estrogen Receptor Signaling Pathway Nuclear Steroid Receptor Activity Negative Regulation Of Cell Population Proliferation Response To Muscle Stretch SMAD Protein Signal Transduction Enzyme Binding Steroid Binding Positive Regulation Of RNA Metabolic Process DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process 14-3-3 Protein Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Population Proliferation Prostate Induction Organ Growth Transcription Coactivator Binding Nuclear Receptor Activity Regulation Of Gene Expression Male Somatic Sex Determination Regulation Of Macromolecule Biosynthetic Process Regulation Of Morphogenesis Of A Branching Structure Transcription Regulator Complex Euchromatin Transcription Cis-regulatory Region Binding Response To Estrogen Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Response To Hormone	None