H3C13 and DNAJC9

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		H3C13	DNAJC9
Description		H3 clustered histone 13	DnaJ heat shock protein family (Hsp40) member C9
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GO Annotations	Cellular Component	Chromatin Nucleosome Extracellular Region Nucleus Nucleoplasm Chromosome Extracellular Exosome	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Protein Folding Chaperone Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity	Protein Binding Heat Shock Protein Binding Histone Binding Protein-folding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Nucleosome Assembly Gene Expression	Nucleosome Assembly Positive Regulation Of ATP-dependent Activity
Pathways		Interleukin-7 signaling Interleukin-7 signaling Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) HDACs deacetylate histones PKMTs methylate histone lysines HDMs demethylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines Chromatin modifying enzymes SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Assembly of the ORC complex at the origin of replication RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination HCMV Early Events HCMV Late Events Transcriptional regulation of granulopoiesis Defective pyroptosis Negative Regulation of CDH1 Gene Transcription Amyloid fiber formation Chromatin modifications during the maternal to zygotic transition (MZT) Factors involved in megakaryocyte development and platelet production MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis Regulation of endogenous retroelements by KRAB-ZFP proteins Regulation of endogenous retroelements by KRAB-ZFP proteins Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: DNAJC9 NASP UHRF1	14 interacting genes: CEBPA H3-5 H3C10 H3C11 H3C12 H3C13 H3C14 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 MORN4
Entrez ID		653604	23234
HPRD ID			13237
Ensembl ID		ENSG00000183598	ENSG00000213551
Uniprot IDs		Q71DI3	Q8WXX5
PDB IDs		2IIJ 2X4W 2X4X 2X4Y 3AV1 3DB3 3MO8 3QO2 3R93 4MZF 4MZG 4MZH 4OUC 5B0Y 5B0Z 5B40 5BO0 5CIU 5VAC 6ACE 6FML 6T79 6T7A 6T7B 6T7C 6T7D 6X59 6X5A 6XJD 6Y5D 6Y5E 7BQZ 7BU9 7JO9 7JOA 7JZV 7PET 7PEU 7PEV 7PEW 7PEX 7PEY 7PEZ 7PF0 7PF2 7PF3 7PF4 7PF5 7PF6 7PFA 7PFC 7PFD 7PFE 7PFF 7PFT 7PFU 7PFV 7PFW 7PFX 7TAN 7U50 7U51 7U52 7U53 7UV9 7UVA 7XCR 7XCT 7XD0 7YRD 8AAG 8ATF 8AV6 8GRQ 8HQY 8HR1 8JLB 8JLD 8OL1 8VMJ 8VMN 8VO0 8VOB 8VWS 8VWT 8VWU 8VWV 8X7I 8X7J 8X7K 9DWF 9DWG 9DWH 9DWI 9DWJ 9DWK 9DWL 9DWM 9GMK 9GMR 9IPU	7CIZ 7CJ0
Enriched GO Terms of Interacting Partners?		Histone Binding Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Histone H3 Ubiquitin Ligase Activity Protein-DNA Complex Assembly Hemi-methylated DNA-binding DNA Damage Sensor Activity DNA Replication-dependent Chromatin Assembly CENP-A Containing Chromatin Assembly Cellular Component Assembly Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Positive Regulation Of ATP-dependent Activity Histone H3K9me2/3 Reader Activity DNA Metabolic Process Blastocyst Development Regulation Of ATP-dependent Activity Protein Folding Chaperone Complex Replication Fork Methyl-CpG Binding Homologous Recombination Response To Testosterone	Structural Constituent Of Chromatin Nucleosome Nucleosome Assembly Nucleosome Organization Protein Heterodimerization Activity Protein-DNA Complex Assembly Gene Expression Telomere Organization Chromosome Cadherin Binding Chromatin Remodeling Epigenetic Regulation Of Gene Expression Chromosome Organization Chromatin Organization Macromolecule Biosynthetic Process Protein-containing Complex DNA Binding Protein-containing Complex Assembly Protein-containing Complex Organization Extracellular Exosome Extracellular Region Cellular Component Assembly Nucleoplasm Organelle Organization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex CHOP-C/EBP Complex White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Response To Phenylpropanoid Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Fat Cell Proliferation Fascia Adherens Actin-based Cell Projection Chromatin Binding
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