MTARC1 and DISP1

		MTARC1	DISP1
Description		mitochondrial amidoxime reducing component 1	dispatched RND transporter family member 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane Nitric-oxide Synthase Complex	Membrane
	Molecular Function	Catalytic Activity Protein Binding Nitrate Reductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Molybdenum Ion Binding Pyridoxal Phosphate Binding Molybdopterin Cofactor Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity Nitrite Reductase Activity	Protein Binding Molecular Carrier Activity
	Biological Process	Nitric Oxide Biosynthetic Process Nitrate Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound	Smoothened Signaling Pathway Patched Ligand Maturation Determination Of Left/right Symmetry Embryonic Pattern Specification Dorsal/ventral Pattern Formation Peptide Transport Diaphragm Development
Pathways		Phase I - Functionalization of compounds
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874)	Heel bone mineral density ( 30598549) Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
Interacting Genes		2 interacting genes: EPHB6 NAA11	1 interacting genes: LAPTM5
Entrez ID		64757	84976
HPRD ID		08653	06326
Ensembl ID		ENSG00000186205	ENSG00000154309
Uniprot IDs		Q5VT66	Q96F81
PDB IDs		6FW2	6XE6 7E2G 7E2H 7E2I
Enriched GO Terms of Interacting Partners?		Detoxification Of Zinc Ion Manganese Ion Export Across Plasma Membrane Calcium:manganese Antiporter Activity Isoleucine-tRNA Ligase Activity Isoleucyl-tRNA Aminoacylation Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Patched Ligand Maturation Protein N-terminal-serine Acetyltransferase Activity Manganese Ion Transmembrane Transporter Activity Intracellular Manganese Ion Homeostasis Manganese Ion Homeostasis Protein-N-terminal Amino-acid Acetyltransferase Activity NatA Complex Zinc Ion Import Into Organelle Manganese Ion Transmembrane Transport Manganese Ion Transport Aminoacyl-tRNA Metabolism Involved In Translational Fidelity Aminoacyl-tRNA Deacylase Activity 9+0 Non-motile Cilium Regulation Of Response To Drug N-terminal Protein Amino Acid Acetylation Diaphragm Development Molecular Carrier Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Cellular Response To Angiotensin Intracellular Copper Ion Homeostasis Monoatomic Cation Transmembrane Transporter Activity Regulation Of Translational Fidelity Protein Maturation Copper Ion Homeostasis Skeletal Muscle Organ Development	Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Negative Regulation Of Autophagic Cell Death Positive Regulation Of Lysosomal Membrane Permeability Regulation Of Lysosomal Membrane Permeability Nitric-oxide Synthase Complex Nitrate Reductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound Nitrate Metabolic Process Molybdenum Ion Binding Nitrite Reductase Activity Molybdopterin Cofactor Binding Nitrite Reductase (NO-forming) Activity Positive Regulation Of Receptor Catabolic Process Defense Response To Tumor Cell Golgi To Lysosome Transport Negative Regulation Of Activated T Cell Proliferation Lysosomal Membrane Organization Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Vacuole Transport Nitric Oxide Biosynthetic Process Positive Regulation Of Macrophage Cytokine Production Negative Regulation Of Interleukin-2 Production Protein Targeting To Lysosome Negative Regulation Of T Cell Receptor Signaling Pathway Nitric Oxide Metabolic Process Positive Regulation Of Membrane Permeability Reactive Nitrogen Species Metabolic Process Negative Regulation Of B Cell Activation Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Regulation Of Activated T Cell Proliferation Regulation Of Macrophage Cytokine Production Positive Regulation Of Interleukin-12 Production Negative Regulation Of Type II Interferon Production Protein Sequestering Activity Protein Targeting To Vacuole Regulation Of T Cell Receptor Signaling Pathway Pyridoxal Phosphate Binding Protein Localization To Lysosome Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Establishment Of Protein Localization To Vacuole Regulation Of Interleukin-2 Production Positive Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Interleukin-12 Production Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Membrane Permeability Negative Regulation Of T Cell Proliferation
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