MRPS25 and CAND2

		MRPS25	CAND2
Description		mitochondrial ribosomal protein S25	cullin associated and neddylation dissociated 2 (putative)
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Nucleus Cytosol
	Molecular Function	Structural Constituent Of Ribosome	Protein Binding TBP-class Protein Binding
	Biological Process	Mitochondrial Translation	SCF Complex Assembly Protein Ubiquitination Positive Regulation Of DNA-templated Transcription
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)	Atrial fibrillation ( 29892015 30061737) Creatine kinase levels ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HOMA-B (corrected for HOMA-IR) ( 30369944) P wave duration ( 28794112) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: ERCC6 UBC	9 interacting genes: CIDEB CNOT3 DNAJB6 FHL2 GLP1R RBX1 SYP TBP UBE3C
Entrez ID		64432	23066
HPRD ID		17594	19120
Ensembl ID		ENSG00000131368	ENSG00000144712
Uniprot IDs		P82663	O75155
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2	8VVY
Enriched GO Terms of Interacting Partners?		Pyrimidine Dimer Repair Response To UV-B Site Of DNA Damage Protein Ubiquitination Protein Modification By Small Protein Conjugation Nucleotide-excision Repair Heteroduplex DNA Loop Binding Nucleotide-excision Repair Factor 2 Complex Post-translational Protein Modification Protein Modification Process Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein DNA Damage Checkpoint Signaling Acetylcholine Catabolic Process In Synaptic Cleft SCF Complex Assembly Extracellular Matrix Structural Constituent XPC Complex Acetylcholine Catabolic Process DNA Damage Sensor Activity Pyrimidine Dimer Repair By Nucleotide-excision Repair Response To UV Signal Transduction In Response To DNA Damage Response To Superoxide Nucleotide-excision Repair Complex DNA Protection Transcription Elongation By RNA Polymerase I Response To Oxygen Radical B-WICH Complex Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Bubble DNA Binding Skeletal Muscle Acetylcholine-gated Channel Clustering Extracellular Matrix Constituent Conferring Elasticity Regulation Of Synaptic Assembly At Neuromuscular Junction Histone Deacetylase Activity, Hydrolytic Mechanism Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair UV-damage Excision Repair Negative Regulation Of Cell Cycle Phase Transition
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