CBLN3 and CBLN1

Number of citations of the paper that reports this interaction (PubMedID 17030622)
45

Data Source:
HPRD (two hybrid, in vivo)

		CBLN3	CBLN1
Description		cerebellin 3 precursor	cerebellin 1 precursor
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Apparatus Synaptic Cleft Synapse Parallel Fiber To Purkinje Cell Synapse	Extracellular Region Plasma Membrane Membrane Extracellular Matrix Synaptic Cleft Synapse Postsynaptic Membrane Parallel Fiber To Purkinje Cell Synapse Trans-synaptic Protein Complex Glutamatergic Synapse
	Molecular Function		Protein Binding Identical Protein Binding
	Biological Process	Maintenance Of Synapse Structure	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Chemical Synaptic Transmission Nervous System Development Synapse Assembly Protein Secretion Cerebellar Granule Cell Differentiation Synapse Organization Establishment Of Localization In Cell Positive Regulation Of Synapse Assembly Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Density Assembly Trans-synaptic Signaling, Modulating Synaptic Transmission Maintenance Of Synapse Structure Positive Regulation Of Long-term Synaptic Depression Regulation Of Presynapse Assembly Negative Regulation Of Inhibitory Synapse Assembly
Pathways
Drugs
Diseases
GWAS		LDL cholesterol ( 20686565 25961943)	Adult body size ( 32376654) Allergic rhinitis ( 31361310) Blood protein levels ( 30072576) Body mass index ( 25673413 28892062) Body size at age 10 ( 32376654) Branched-chain amino acid levels (Isoleucine) ( 27898682) Fasting glucose ( 34074324) Pursuit maintenance gain ( 29064472) Social autistic-like traits ( 24133439)
Interacting Genes		3 interacting genes: CBLN1 CBLN2 CBLN4	1 interacting genes: CBLN3
Entrez ID		643866	869
HPRD ID		19198	02697
Ensembl ID		ENSG00000139899	ENSG00000102924
Uniprot IDs		Q6UW01	P23435
PDB IDs			5KC5 5KC6 5KC7 5KCA
Enriched GO Terms of Interacting Partners?		Trans-synaptic Signaling, Modulating Synaptic Transmission Synaptic Cleft Synapse Assembly Trans-synaptic Protein Complex Cell Junction Assembly Synapse Organization Maintenance Of Synapse Structure Trans-synaptic Signaling Synaptic Signaling Cell Junction Organization Modulation Of Chemical Synaptic Transmission Cell Junction Maintenance Positive Regulation Of Synapse Assembly Glutamatergic Synapse Cell-cell Signaling Cellular Component Maintenance Signaling Cell Communication Positive Regulation Of Cell Junction Assembly Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Synapse Negative Regulation Of Inhibitory Synapse Assembly Regulation Of Synapse Assembly Spontaneous Synaptic Transmission Regulation Of Cell Junction Assembly Positive Regulation Of Nervous System Development Regulation Of Inhibitory Synapse Assembly Regulation Of Synapse Organization Chemical Synaptic Transmission Cerebellar Granule Cell Differentiation Positive Regulation Of Long-term Synaptic Depression Secretion By Cell Extracellular Matrix Negative Regulation Of Synapse Assembly Extracellular Region Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Nervous System Development Secretion Positive Regulation Of Cellular Component Biogenesis Regulation Of Long-term Synaptic Depression Negative Regulation Of Synapse Organization Glutamatergic Neuron Differentiation Regulation Of Postsynaptic Density Assembly Cellular Component Assembly Regulation Of Postsynaptic Specialization Assembly Regulation Of Excitatory Synapse Assembly Cell Differentiation In Hindbrain Parallel Fiber To Purkinje Cell Synapse	Maintenance Of Synapse Structure Parallel Fiber To Purkinje Cell Synapse Synaptic Cleft Cell Junction Maintenance Cellular Component Maintenance Synapse Organization
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