RPS21 and ZUFSP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RPS21	ZUFSP
Gene Name		ribosomal protein S21	zinc finger with UFM1-specific peptidase domain
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Small Ribosomal Subunit Cytosolic Small Ribosomal Subunit
	Molecular Function	Structural Constituent Of Ribosome Poly(A) RNA Binding Protein N-terminus Binding	Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Small Subunit Biogenesis Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		4 interactors: APP LBP RPSA ZUFSP	4 interactors: CLN8 PRMT5 RPS21 SHCBP1
Entrez ID		6227	221302
HPRD ID		01605	12840
Ensembl ID		ENSG00000171858	ENSG00000153975
Uniprot IDs		P63220 Q6FGH5	Q96AP4
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		RNA 3'-end Processing Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response RRNA Export From Nucleus Lipopolysaccharide Transport Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Collateral Sprouting Axon Midline Choice Point Recognition RRNA Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis RRNA 3'-end Processing Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Axon Choice Point Recognition Positive Regulation Of Respiratory Burst Neuron Remodeling Ribosomal Small Subunit Assembly Opsonization Regulation Of Respiratory Burst Macrophage Activation Involved In Immune Response Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Macrophage Activation MRNA Metabolic Process Positive Regulation Of Toll-like Receptor Signaling Pathway RNA Processing Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Lipoteichoic Acid Detection Of Molecule Of Bacterial Origin Chemotaxis Regulation Of Growth Maturation Of 5.8S RRNA Leukocyte Migration Involved In Inflammatory Response Endocytosis Cellular Copper Ion Homeostasis Regulation Of Tumor Necrosis Factor Biosynthetic Process Cell Activation Copper Ion Homeostasis Suckling Behavior Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Macrophage Activation Positive Regulation Of Granulocyte Chemotaxis Negative Regulation Of Growth Of Symbiont In Host Innate Immune Response Ribosome Assembly Detection Of Biotic Stimulus Maturation Of SSU-rRNA	Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine L-glutamate Uptake Involved In Synaptic Transmission Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Age-dependent Response To Oxidative Stress RRNA 3'-end Processing Ribonucleoprotein Complex Biogenesis Somatic Motor Neuron Differentiation L-glutamate Import Histone H4-R3 Methylation Endothelial Cell Activation Neurotransmitter Uptake Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) NcRNA Metabolic Process Neurofilament Cytoskeleton Organization Neuromuscular Process Controlling Posture Peptidyl-arginine N-methylation Amino Acid Import Maturation Of 5.8S RRNA MRNA Metabolic Process Histone Arginine Methylation RNA Processing Peptidyl-arginine Methylation Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) L-glutamate Transport Maturation Of SSU-rRNA Photoreceptor Cell Maintenance Ribosomal Small Subunit Biogenesis Intermediate Filament Cytoskeleton Organization Social Behavior Spliceosomal SnRNP Assembly Intermediate Filament-based Process Musculoskeletal Movement Cellular Macromolecule Catabolic Process Membrane Organization Spinal Cord Motor Neuron Differentiation Adult Walking Behavior Ceramide Biosynthetic Process Lysosome Organization Ventral Spinal Cord Development Retina Homeostasis Mitochondrial Membrane Organization
Tagcloud ?		a1bg akr1c ambp anxa2 eef1g eif4a1 elucidating eno1 est ests fn1 ftl gnb2l1 gpx4 hcc id1 krt8 ldha libraries rpl10 rpl13a rpl4 rpl9 rplp0 rps10 rps15 serpinc1 vim virological
Tagcloud (Difference) ?		a1bg akr1c ambp anxa2 eef1g eif4a1 elucidating eno1 est ests fn1 ftl gnb2l1 gpx4 hcc id1 krt8 ldha libraries rpl10 rpl13a rpl4 rpl9 rplp0 rps10 rps15 serpinc1 vim virological
Tagcloud (Intersection) ?