RPS5 and RPS4X

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (pull down, biochemical, biochemical)

		RPS5	RPS4X
Gene Name		ribosomal protein S5	ribosomal protein S4, X-linked
Image
Gene Ontology Annotations	Cellular Component	Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome	Cytosol Ribosome Polysome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding	Structural Constituent Of Ribosome RRNA Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translational Fidelity SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organismal Development Positive Regulation Of Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Positive Regulation Of Translation
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: RPS4X	11 interactors: ARPC3 CAMK2D CTBP2 HNRNPH3 MCM2 RPS15 RPS5 RPS6 RPS7 RPS8 RPS9
Entrez ID		6193	6191
HPRD ID		04695	02427
Ensembl ID		ENSG00000083845
Uniprot IDs		M0QZN2 P46782	B2R491 P62701
PDB IDs		3J3A	3J3A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translation Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Translational Termination Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Protein Targeting To Membrane Translational Elongation RNA Catabolic Process Cellular Protein Complex Disassembly Viral Life Cycle	Viral Life Cycle Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Translational Termination Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Protein Targeting To Membrane Translational Elongation RNA Catabolic Process Cellular Protein Complex Disassembly Protein Complex Disassembly Establishment Of Protein Localization To Membrane Translational Initiation MRNA Metabolic Process Viral Process Ribosomal Small Subunit Biogenesis Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Aromatic Compound Catabolic Process Protein Localization To Organelle Translation Cytoplasmic Transport RRNA Processing RRNA Metabolic Process Cellular Macromolecule Catabolic Process Membrane Organization Ribosome Biogenesis Intracellular Protein Transport Ribonucleoprotein Complex Biogenesis Ribosomal Small Subunit Assembly Cellular Protein Localization RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Protein Transport Establishment Of Protein Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression RNA Biosynthetic Process Intracellular Transport Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Translational Fidelity Macromolecule Biosynthetic Process
Tagcloud ?		agricultural ancient avrpphb avrpphb2 balanced coevolved coevolving confers defence diffusely durable explains facultative fail globally homologues incurs lived maintained pair pathogen persist polymorphism recognizes ref syringae thaliana tightly ubiquitous	aberrant blastocyst bovine cattle clones cows embryo embryos freemartin gestation hatched hprt inner lost mecp2 pregnancies recipient reconstructed rq scnt slc25a6 somatic telomerase transcript transfer twin xiap xist zfx
Tagcloud (Difference) ?		agricultural ancient avrpphb avrpphb2 balanced coevolved coevolving confers defence diffusely durable explains facultative fail globally homologues incurs lived maintained pair pathogen persist polymorphism recognizes ref syringae thaliana tightly ubiquitous	aberrant blastocyst bovine cattle clones cows embryo embryos freemartin gestation hatched hprt inner lost mecp2 pregnancies recipient reconstructed rq scnt slc25a6 somatic telomerase transcript transfer twin xiap xist zfx
Tagcloud (Intersection) ?