RPL31 and GPR20

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RPL31	GPR20
Description		ribosomal protein L31	G protein-coupled receptor 20
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Ribosome Focal Adhesion Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse Extracellular Exosome Ribonucleoprotein Complex	Plasma Membrane Membrane Receptor Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	G Protein-coupled Receptor Activity
	Biological Process	Cytoplasmic Translation Translation	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	G alpha (s) signalling events
Drugs
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)	Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27618447 27841878 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27618447 27841878 28498854 31217584)
Interacting Genes		12 interacting genes: APP BLVRB BRCA1 CACNA1A CRKL DUX4 EIF4ENIF1 EWSR1 FOXP1 GPR20 IL7R PTEN	3 interacting genes: JAM2 POLR1H RPL31
Entrez ID		6160	2843
HPRD ID		17994	03550
Ensembl ID		ENSG00000071082	ENSG00000204882
Uniprot IDs		P62899	Q59GP3 Q99678
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7XNX 7XNY 8A3D 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO	8HS2 8HS3 8HSC
Enriched GO Terms of Interacting Partners?		Regulation Of Growth Postsynaptic Specialization Assembly Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Negative Regulation Of Gene Expression Regulation Of Developmental Process Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Cell Population Proliferation Amylin Binding Hemopoiesis Negative Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Signal Transduction Response To Peptide Cellular Response To Amyloid-beta Response To Cytokine Dendrite Development Regulation Of Cell Communication Regulation Of T Cell Migration Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Cell Communication Reproductive Behavior Regulation Of Signaling Positive Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Riboflavin Reductase (NADPH) Activity FMN Reductase (NADPH) Activity FMN Reductase (NADH) Activity Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Growth Postsynaptic Specialization Organization Negative Regulation Of Lymphocyte Apoptotic Process Negative Regulation Of Leukocyte Apoptotic Process Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Organ Growth Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Lymphocyte Apoptotic Process Response To Amyloid-beta Regulation Of Gene Expression Positive Regulation Of Biosynthetic Process Negative Regulation Of Cell Cycle Process Macrophage Activation Acetylcholine Receptor Activator Activity Regulation Of Macromolecule Biosynthetic Process Cellular Developmental Process Myeloid Cell Development Chemical Synaptic Transmission Regulation Of Nucleobase-containing Compound Metabolic Process	Termination Of RNA Polymerase I Transcription Hematopoietic Stem Cell Migration To Bone Marrow Protein Complex Involved In Cell Adhesion Lymphocyte Aggregation Large Ribosomal Subunit RNA Polymerase I Complex DNA-templated Transcription Termination Negative Regulation Of Nervous System Process Leukocyte Aggregation Negative Regulation Of Myelination Somatodendritic Compartment Hematopoietic Stem Cell Migration Leukocyte Tethering Or Rolling Cellular Extravasation Leukocyte Adhesion To Vascular Endothelial Cell Cell-cell Contact Zone DNA-directed RNA Polymerase Activity Maintenance Of Blood-brain Barrier DNA-directed RNA Polymerase Complex Tight Junction Positive Regulation Of Lymphocyte Migration Regulation Of Myelination Cytosolic Large Ribosomal Subunit Leukocyte Cell-cell Adhesion
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