RPL19 and COX11

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPL19	COX11
Gene Name		ribosomal protein L19	COX11 cytochrome c oxidase copper chaperone
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding	Cytochrome-c Oxidase Activity Copper Ion Binding Electron Carrier Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Respiratory Gaseous Exchange Respiratory Chain Complex IV Assembly Negative Regulation Of Glucokinase Activity Hydrogen Ion Transmembrane Transport
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport Orphan transporters
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		3 interactors: COX11 TERF1 YWHAQ	1 interactors: RPL19
Entrez ID		6143	1353
HPRD ID		01594	04709
Ensembl ID		ENSG00000108298	ENSG00000166260
Uniprot IDs		J3KTE4 P84098	B4DEY8 B4DI26 Q9Y6N1
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Transferase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Glucokinase Activity Positive Regulation Of Organelle Organization Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Respiratory Chain Complex IV Assembly Positive Regulation Of Apoptotic Process Regulation Of Telomerase Activity Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Telomere Maintenance RNA-dependent DNA Replication Cytochrome Complex Assembly Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Microtubule Polymerization Telomere Maintenance Via Telomere Lengthening Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitotic Spindle Assembly Checkpoint Regulation Of Organelle Organization Spindle Assembly Checkpoint Substantia Nigra Development Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Protein Complex Assembly Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Neural Nucleus Development Respiratory Gaseous Exchange Positive Regulation Of Mitochondrion Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process	Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Translational Termination Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Protein Targeting To Membrane Translational Elongation RNA Catabolic Process Cellular Protein Complex Disassembly Viral Life Cycle Protein Complex Disassembly Establishment Of Protein Localization To Membrane Translational Initiation
Tagcloud ?		amplification certain copy cytotoxic eif2alpha endoplasmic eukaryotic exert incubated inducing mcf7 mediate overexpressed overexpressing overexpression p38 perk physiological pleiotropic reticulum ribosomal sensitized sensitizing stress unfolded upr upregulation variation	6448dup brca1 brca2 ccnd1 discovery fgfr2 focused great history importance malignancy manage members moderate modifiers modify numa1 polygenic polymorphisms predictor search slc4a7 strongest tnrc9 today transmission variant variants whose
Tagcloud (Difference) ?		amplification certain copy cytotoxic eif2alpha endoplasmic eukaryotic exert incubated inducing mcf7 mediate overexpressed overexpressing overexpression p38 perk physiological pleiotropic reticulum ribosomal sensitized sensitizing stress unfolded upr upregulation variation	6448dup brca1 brca2 ccnd1 discovery fgfr2 focused great history importance malignancy manage members moderate modifiers modify numa1 polygenic polymorphisms predictor search slc4a7 strongest tnrc9 today transmission variant variants whose
Tagcloud (Intersection) ?