FKBP10 and MRPL45

		FKBP10	MRPL45
Description		FKBP prolyl isomerase 10	mitochondrial ribosomal protein L45
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Intermembrane Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	In Utero Embryonic Development Protein Folding Collagen Fibril Organization Aorta Morphogenesis Wound Healing Extracellular Matrix Assembly	Mitochondrial Translation
Pathways
Drugs
Diseases		Bruck syndrome
GWAS		Appendicular lean mass ( 33097823) Eosinophil count ( 32888494)	Ovarian cancer ( 23535730)
Interacting Genes		4 interacting genes: CDC42 ELN OGT SLC2A4	6 interacting genes: CAVIN1 EMD PFDN5 PLEKHA3 PRKN TRIM23
Entrez ID		60681	84311
HPRD ID		09522	14764
Ensembl ID		ENSG00000141756	ENSG00000278845
Uniprot IDs		Q8NAG5 Q96AY3	A0A087WU62 A0A087X2D5 B4DEF8
PDB IDs
Enriched GO Terms of Interacting Partners?		Circulatory System Process Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly	Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Amyloid Fibril Formation Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway TMEM240-body Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Positive Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Glucokinase Activity Regulation Protein Catabolic Process At Presynapse Negative Regulation Of Intralumenal Vesicle Formation Mitochondrion To Lysosome Vesicle-mediated Transport Mitochondrion-derived Vesicle F-box Domain Binding Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Hydrogen Sulfide Negative Regulation Of Spontaneous Neurotransmitter Secretion Response To Curcumin RNA Polymerase III Assembly RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly Termination Of RNA Polymerase I Transcription RRNA Primary Transcript Binding Positive Regulation Of Intracellular Transport Golgi Membrane Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To L-glutamine Response To Hydrogen Sulfide Negative Regulation Of Exosomal Secretion Endoplasmic Reticulum Negative Regulation Of Supramolecular Fiber Organization Positive Regulation Of Autophagy Lewy Body Regulation Of Spontaneous Synaptic Transmission Type 2 Mitophagy Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Mitochondrial Fission Regulation Of Endosome Organization Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Positive Regulation Of Neurotransmitter Uptake Regulation Of Synaptic Vesicle Transport Free Ubiquitin Chain Polymerization Cellular Response To Dopamine Negative Regulation Of Mitochondrial Fusion Protein-containing Complex Negative Regulation Of Neurotransmitter Secretion Regulation Of Retrograde Transport, Endosome To Golgi
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