RGS13 and APOL6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RGS13	APOL6
Description		regulator of G protein signaling 13	apolipoprotein L6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Extracellular Region Cytoplasm
	Molecular Function	GTPase Activity Protein Binding	Protein Binding Lipid Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of G Protein-coupled Receptor Signaling Pathway	Lipid Transport Lipoprotein Metabolic Process
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Height ( 28552196) Metabolite levels ( 23823483) Response to quetiapine in schizophrenia ( 29503163)	HDL cholesterol levels ( 32203549) Triglyceride levels ( 32203549) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: APOL6 CFTR CREB1 GNAQ MTDH PRKACA	10 interacting genes: ADAMTSL4 CCN3 FNTB GMCL1 KPNA3 KRTAP10-8 LAMTOR3 MTNR1B RGS13 TEPSIN
Entrez ID		6003	80830
HPRD ID		06222	06266
Ensembl ID		ENSG00000127074	ENSG00000221963
Uniprot IDs		O14921	B3KTP4 Q9BWW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Body Fluid Levels CAMP/PKA Signal Transduction Cellular Response To Forskolin Response To Forskolin Sperm Capacitation Positive Regulation Of Hormone Secretion Response To Glucagon Multicellular Organismal-level Water Homeostasis Response To Ketone Regulation Of Hormone Secretion Response To Alcohol Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Multicellular Organismal-level Chemical Homeostasis Regulation Of Steroid Biosynthetic Process Chemotaxis To Arachidonate Positive Regulation Of Insulin Secretion Regulation Of Hormone Levels Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Anion Channel Activity Positive Regulation Of Peptide Secretion Regulation Of Secretion By Cell Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Lipid Biosynthetic Process Regulation Of Steroid Metabolic Process Regulation Of Multicellular Organismal Process Response To Purine-containing Compound Regulation Of Secretion Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Protein Secretion Response To Dehydroepiandrosterone Response To Hormone Positive Regulation Of Lipid Metabolic Process Cell Maturation Regulation Of Insulin Secretion Positive Regulation Of Enamel Mineralization ATF4-CREB1 Transcription Factor Complex Response To Hypobaric Hypoxia Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell Communication Response To Lipid Transepithelial Water Transport	Negative Regulation Of Nervous System Process Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion Pigment Cell Development Coated Vesicle Membrane Negative Regulation Of Hormone Secretion Negative Regulation Of Protein Secretion Protein Farnesyltransferase Complex Protein Farnesyltransferase Activity Protein Prenyltransferase Activity Protein Farnesylation Viral Penetration Into Host Nucleus Melatonin Receptor Activity Negative Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Transport Regulation Of Nervous System Process Regulation Of Neuronal Action Potential Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Sensory Perception Of Pain Endothelial Cell-cell Adhesion Bone Regeneration Ragulator Complex Intracellular Transport Of Virus Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Insulin Secretion Negative Regulation Of Secretion Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Secretion By Cell Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Monocyte Chemotaxis Smooth Muscle Cell Proliferation FNIP-folliculin RagC/D GAP Interstitial Matrix Protein Prenylation Host Cell Prenyltransferase Activity NLS-dependent Protein Nuclear Import Complex Regulation Of Peptide Hormone Secretion Acetyltransferase Activator Activity Endothelial Cell Chemotaxis
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