PVT1 and KRT9

Number of citations of the paper that reports this interaction (PubMedID 31699956)
42

Data Source:
BioGRID (unspecified method)

		PVT1	KRT9
Description		Pvt1 oncogene	keratin 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Nucleus Cytosol Cytoskeleton Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function		Structural Molecule Activity Structural Constituent Of Cytoskeleton Structural Constituent Of Skin Epidermis
	Biological Process		Morphogenesis Of An Epithelium Spermatogenesis Epidermis Development Epithelial Cell Differentiation Skin Development Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs			Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Epidermolytic palmoplantar keratoderma (EPPK)
GWAS		Allergic sensitization ( 30013184 23817571) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 33097823) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Basophil count ( 32888494) Bell's palsy ( 33602968) Celiac disease and Rheumatoid arthritis ( 26546613) Crohn's disease ( 32581322) Diffuse large B cell lymphoma ( 25261932) End-stage renal disease ( 17395743) Eosinophil count ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Follicular lymphoma ( 25279986) Graft survival time in renal transplantation (donor effect) x APOL1 genotype interaction ( 32080893) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hodgkin's lymphoma ( 21037568) Immunoglobulin A ( 20694011) Lung cancer ( 28604730) Lymphocyte count ( 27863252 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Medication use (thyroid preparations) ( 31015401) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Multiple sclerosis ( 21833088 31604244) Neutrophil count ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Orofacial clefts ( 19270707) Pancreatic cancer ( 25086665) Platelet count ( 32888494) Plateletcrit ( 27863252 32888494) Psychosis (atypical) ( 24132900) Renal cell carcinoma ( 24220699) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Rheumatoid arthritis ( 24390342 30423114) Seasonality ( 25562672) Selective IgA deficiency ( 27723758) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 28714469) Type 2 diabetes ( 30297969) Urinary bladder cancer ( 24861552) Urinary calcium excretion ( 31993563) Waist-hip ratio ( 28552196) White blood cell count ( 27863252 32888494)
Interacting Genes		7 interacting genes: ERG HSP90B1 KRT9 NOP2 POTEKP RBM25 RPS16	7 interacting genes: ADAM3B DANCR OGT PVT1 UBE3A WBP2 YWHAQ
Entrez ID		5820	3857
HPRD ID			06351
Ensembl ID		ENSG00000249859	ENSG00000171403
Uniprot IDs			P35527
PDB IDs
Enriched GO Terms of Interacting Partners?			Progesterone Receptor Signaling Pathway Response To Progesterone Sperm Entry Positive Regulation Of TORC1 Signaling Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Golgi Lumen Acidification Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of TOR Signaling Chromatin DNA Binding Nuclear Receptor-mediated Signaling Pathway Regulation Of TORC1 Signaling Regulation Of Golgi Lumen Acidification Protein O-acetylglucosaminyltransferase Activity Response To Hormone Hormone-mediated Signaling Pathway Regulation Of TOR Signaling Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Cellular PH Reduction Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Protein Ubiquitination Response To Ketone Intracellular Signal Transduction Response To Steroid Hormone Carbon Catabolite Regulation Of Transcription Regulation Of Post-translational Protein Modification Prostate Gland Growth Intracellular Receptor Signaling Pathway Regulation Of Transcription By Glucose Establishment Of Protein Localization To Chromatin Rhythmic Process Cellular Response To Nutrient Levels NSL Complex Transcription Coactivator Activity Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway
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