SLAMF7 and PANK1

		SLAMF7	PANK1
Description		SLAM family member 7	pantothenate kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Nucleus Nucleolus Cytoplasm Endosome Cytosol Clathrin-coated Vesicle Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	Identical Protein Binding	Nucleotide Binding Pantothenate Kinase Activity ATP Binding Kinase Activity Transferase Activity Protein Homodimerization Activity Acetyl-CoA Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Cell Adhesion Natural Killer Cell Activation T Cell Activation Natural Killer Cell Mediated Cytotoxicity Innate Immune Response	Coenzyme A Biosynthetic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Coenzyme A biosynthesis
Drugs		Elotuzumab
Diseases
GWAS		Blood protein levels ( 30072576) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)	Distal colorectal cancer ( 33632709) Distal/Left-sided colorectal cancer ( 33632709) Metabolic traits ( 19060910) Plateletcrit ( 32888494)
Interacting Genes		4 interacting genes: CLK3 MAK SH2D1A TRIB2	2 interacting genes: ACADM YWHAQ
Entrez ID		57823	53354
HPRD ID		09432	07549
Ensembl ID		ENSG00000026751	ENSG00000152782
Uniprot IDs		B4DVL7 B4DW98 Q9NQ25	A0A8C8KBT8 Q8TE04
PDB IDs			2I7N 3SMP
Enriched GO Terms of Interacting Partners?		Cytoplasm Negative Regulation Of Uterine Smooth Muscle Contraction Alpha-1B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Phospholipase C-activating Adrenergic Receptor Signaling Pathway Protein Homodimerization Activity Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Protein Phosphorylation Negative Regulation Of Non-motile Cilium Assembly Skeletal Muscle Tissue Development Left Lung Morphogenesis Superior Vena Cava Morphogenesis Prolactin Secreting Cell Differentiation Cell Proliferation Involved In Outflow Tract Morphogenesis Pulmonary Vein Morphogenesis Subthalamic Nucleus Development Regulation Of Actin Filament Depolymerization Actin Filament Capping Negative Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Pantothenate Kinase Activity Regulation Of Protein Depolymerization Actin Filament-based Process Alpha2-adrenergic Receptor Activity Phosphorylation Pulmonary Myocardium Development Endodermal Digestive Tract Morphogenesis Deltoid Tuberosity Development Norepinephrine Binding Thermoception Somatotropin Secreting Cell Differentiation Cell Proliferation Involved In Heart Morphogenesis Acetyl-CoA Binding Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Negative Regulation Of Epinephrine Secretion Protein Kinase Activity Striated Muscle Tissue Development Embryonic Heart Tube Left/right Pattern Formation Muscle Structure Development Extraocular Skeletal Muscle Development Atrioventricular Valve Development Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Ubiquitin-protein Transferase Regulator Activity Pointed-end Actin Filament Capping	Carnitine Metabolic Process, CoA-linked Medium-chain Fatty Acyl-CoA Dehydrogenase Activity Medium-chain Fatty Acid Catabolic Process Carnitine Biosynthetic Process Identical Protein Binding Carnitine Metabolic Process Medium-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Acyl-CoA Dehydrogenase Activity Glycogen Biosynthetic Process Amino-acid Betaine Metabolic Process Polysaccharide Biosynthetic Process Oxidoreductase Activity, Acting On The CH-CH Group Of Donors
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