COG6 and CSRP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COG6	CSRP2
Description		component of oligomeric golgi complex 6	cysteine and glycine rich protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Nucleus Cytoplasm Focal Adhesion Z Disc
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Muscle Actinin Binding Metal Ion Binding
	Biological Process	Retrograde Transport, Vesicle Recycling Within Golgi Intra-Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Glycosylation	Cell Differentiation Sarcomere Organization Muscle Tissue Development
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Asthma ( 32296059 31959851 30929738) Asthma (adult onset) ( 30929738) Eosinophil count ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Height ( 31562340) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Psoriasis ( 25903422 18369459) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676 23143596) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Adult asthma ( 27611488) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		64 interacting genes: ARHGEF5 ATXN7 BAIAP2 BCL10 CCDC116 CCDC120 CCDC187 CCDC92 CNN1 CNNM3 CSRP2 CUL5 DOCK8 DRC4 FAM110A FAM90A1 FANCG FNDC11 GEM GOLGA2 GRAP2 IGFN1 KANK2 LGALS14 LMO4 MCM7 MFAP1 MRI1 NDUFA5 NEK6 NTAQ1 NUP58 OAS1 PLEKHA2 POM121 PPP1R18 PSMA1 PSMB1 QARS1 RAB3IL1 RAB6B RSPH14 RTP5 RUNX1T1 SAXO4 SCNM1 SMARCD1 SNAI1 SNRPB SPG21 SYCP2L SYT17 TBC1D22B TMSB4X TSC1 TSGA10 TSHZ3 TSNAX TTC7B UFSP1 WASHC3 ZBTB16 ZFC3H1 ZNF417	8 interacting genes: ARC COG6 EEF1A1 KAT14 PIAS1 TRIM23 TRIM27 UBC
Entrez ID		57511	1466
HPRD ID		08445	03523
Ensembl ID		ENSG00000133103	ENSG00000175183
Uniprot IDs		A0A140VJG7 Q9Y2V7	A0A024RBB5 F8VW96 Q16527
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Vesicle-mediated Transport Positive Regulation Of Catabolic Process SUMO Transferase Activity Protein Modification By Small Protein Conjugation Positive Regulation Of Transcytosis Alpha-2 Macroglobulin Receptor Activity Apolipoprotein Receptor Activity Protein Sumoylation Virus-like Capsid Post-translational Protein Modification Regulation Of Autophagy Regulation Of Protein Catabolic Process Endocytic Vesicle Membrane Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Reverse Cholesterol Transport Regulation Of Transcytosis Lipoprotein Particle Receptor Binding PML Body Vesicle-mediated Intercellular Transport Eukaryotic Translation Elongation Factor 1 Complex Astrocyte Activation Involved In Immune Response Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
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