PTGDR and ANKRD13C

Number of citations of the paper that reports this interaction (PubMedID 23762421)
97

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		PTGDR	ANKRD13C
Description		prostaglandin D2 receptor	ankyrin repeat domain 13C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Prostaglandin J Receptor Activity G Protein-coupled Receptor Activity Prostaglandin D Receptor Activity Protein Binding	Signaling Receptor Binding Protein Binding Protein Carrier Chaperone
	Biological Process	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Male Sex Determination Sleep Mast Cell Degranulation Adenosine Metabolic Process Cellular Response To Prostaglandin D Stimulus	Protein Targeting To Membrane Cellular Response To Prostaglandin D Stimulus Regulation Of Anoikis
Pathways		Prostanoid ligand receptors G alpha (s) signalling events
Drugs		Treprostinil Nedocromil
Diseases
GWAS		Fasting glucose ( 34059833)
Interacting Genes		4 interacting genes: ANKRD13C APP GGA3 GNAS	2 interacting genes: CLDND2 PTGDR
Entrez ID		5729	81573
HPRD ID		05254	13176
Ensembl ID		ENSG00000168229	ENSG00000118454
Uniprot IDs		Q13258	Q8N6S4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Catecholamine Stimulus Response To Catecholamine Cellular Response To Prostaglandin Stimulus Regulation Of Amyloid Precursor Protein Catabolic Process Cellular Localization Regulation Of Multicellular Organism Growth Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Trans-Golgi Network Membrane Amylin Binding Positive Regulation Of Toll Signaling Pathway Perinuclear Region Of Cytoplasm Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cellular Response To Oxygen-containing Compound Recycling Endosome Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Mu-type Opioid Receptor Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Early Endosome Membrane Axon Midline Choice Point Recognition Positive Regulation Of Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Hair Follicle Placode Formation Corticotropin-releasing Hormone Receptor 1 Binding Adenylate Cyclase Activator Activity Adenylate Cyclase-activating Serotonin Receptor Signaling Pathway Adenylate Cyclase Regulator Activity Response To Ketone Establishment Of Protein Localization To Membrane	Prostaglandin J Receptor Activity Prostaglandin D Receptor Activity Type II Interferon-mediated Signaling Pathway Growth Hormone Receptor Binding Cellular Response To Interleukin-7 Interleukin-10-mediated Signaling Pathway Interleukin-11-mediated Signaling Pathway Interleukin-15-mediated Signaling Pathway Interleukin-4-mediated Signaling Pathway Interleukin-2-mediated Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT Response To Interleukin-7 Interleukin-9-mediated Signaling Pathway T-helper 17 Cell Lineage Commitment Type III Interferon-mediated Signaling Pathway Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane CCR5 Chemokine Receptor Binding Interleukin-7-mediated Signaling Pathway Sleep Adenosine Metabolic Process Male Sex Determination Cellular Response To Prostaglandin D Stimulus Interleukin-6-mediated Signaling Pathway T-helper Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Positive Regulation Of Homotypic Cell-cell Adhesion Alpha-beta T Cell Lineage Commitment Protein Localization To Cell-cell Junction CD4-positive, Alpha-beta T Cell Lineage Commitment Growth Hormone Receptor Signaling Pathway Cellular Response To Prostaglandin Stimulus Sex Determination Mast Cell Degranulation Purine Nucleoside Metabolic Process Positive Regulation Of Sprouting Angiogenesis T Cell Lineage Commitment Response To Antibiotic Leukocyte Degranulation Non-membrane Spanning Protein Tyrosine Kinase Activity Nucleoside Metabolic Process Type I Interferon-mediated Signaling Pathway Regulation Of Sprouting Angiogenesis Lysosome Localization Cell Surface Receptor Signaling Pathway Via JAK-STAT Interferon-mediated Signaling Pathway Cellular Response To Virus Cell Surface Receptor Signaling Pathway Via STAT
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