APMAP and RASA4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		APMAP	RASA4
Description		adipocyte plasma membrane associated protein	RAS p21 protein activator 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Surface Membrane	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Arylesterase Activity Protein Binding	GTPase Activator Activity Phospholipid Binding Zinc Ion Binding Metal Ion Binding
	Biological Process		Negative Regulation Of GTPase Activity Intracellular Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Cellular Response To Calcium Ion Regulation Of Intracellular Signal Transduction
Pathways			Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Chronotype ( 27494321) Morning vs. evening chronotype ( 27494321) Type 2 diabetes ( 32499647)
Interacting Genes		5 interacting genes: FAM209A LOXL3 OGT RASA4 SMAD3	5 interacting genes: APMAP ERBB3 HRAS JPT2 OVGP1
Entrez ID		57136	10156
HPRD ID		09840	12135
Ensembl ID		ENSG00000101474	ENSG00000105808
Uniprot IDs		Q9HDC9	E7ERK1 O43374
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin DNA Binding Cellular Response To Carbohydrate Stimulus Negative Regulation Of Lung Blood Pressure Nuclear Inner Membrane Nuclear Mineralocorticoid Receptor Binding Cellular Response To Glucose Stimulus Intracellular Glucose Homeostasis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Sterol Response Element Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Paraxial Mesoderm Morphogenesis Response To Glucose Negative Regulation Of Protein Catabolic Process Response To Monosaccharide Protein O-acetylglucosaminyltransferase Activity Peptidyl-lysine Oxidation Fibronectin Fibril Organization Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Carbohydrate Carbohydrate Homeostasis Glucose Homeostasis Pericardium Development Regulation Of Lung Blood Pressure Mesoderm Morphogenesis Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein-lysine 6-oxidase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor Protein Oxidation Transdifferentiation SMAD Protein Complex Trophoblast Cell Migration Carbon Catabolite Regulation Of Transcription Negative Regulation Of T-helper 17 Cell Lineage Commitment DEAD/H-box RNA Helicase Binding Heteromeric SMAD Protein Complex Epithelium Development Regulation Of Transforming Growth Factor Beta2 Production Negative Regulation Of Developmental Process Regulation Of Transcription By Glucose Regulation Of Cell Junction Assembly Positive Regulation Of Extracellular Matrix Assembly Embryonic Foregut Morphogenesis Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress NSL Complex Microtubule Anchoring At Centrosome	Schwann Cell Development Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuron Apoptotic Process Glial Cell Development Regulation Of Calcium-mediated Signaling Myelination Axon Ensheathment GTPase Complex Perivitelline Space ErbB-3 Class Receptor Binding Neuregulin Receptor Activity Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Negative Regulation Of Neuron Apoptotic Process Phospholipase C Activator Activity Negative Regulation Of Binding Of Sperm To Zona Pellucida Chitin Metabolic Process Regulation Of Binding Of Sperm To Zona Pellucida Chitin Catabolic Process Chitinase Activity Egg Coat Arylesterase Activity Positive Regulation Of Epithelial Cell Proliferation Schwann Cell Differentiation Oncogene-induced Cell Senescence Chitin Binding ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Neuron Apoptotic Process T-helper 1 Type Immune Response Negative Regulation Of Motor Neuron Apoptotic Process Endocardial Cushion Development Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Apoptotic Signaling Pathway Positive Regulation Of Ruffle Assembly Endocytosis Involved In Viral Entry Into Host Cell Protein Tyrosine Kinase Activator Activity
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