CABP4 and PACS1

		CABP4	PACS1
Description		calcium binding protein 4	phosphofurin acidic cluster sorting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Cell Projection Terminal Bouton Synapse Presynapse	Golgi Apparatus Cytosol COPI-coated Vesicle
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Transmembrane Transporter Binding Metal Ion Binding	Protein Binding Transmembrane Transporter Binding
	Biological Process	Signal Transduction Visual Perception Phototransduction Photoreceptor Cell Morphogenesis Retinal Cone Cell Development Retinal Bipolar Neuron Differentiation	Lymphocyte Homeostasis Protein Localization To Golgi Apparatus Protein Localization To Plasma Membrane
Pathways			Nef mediated downregulation of MHC class I complex cell surface expression
Drugs
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS		Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278)	Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756 33263727 34002096) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		6 interacting genes: BCL6 CACNA1F IKZF3 LNX2 MFHAS1 TLE5	10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4
Entrez ID		57010	55690
HPRD ID		12344	06320
Ensembl ID		ENSG00000175544	ENSG00000175115
Uniprot IDs		P57796	Q6VY07
PDB IDs
Enriched GO Terms of Interacting Partners?			Response To Metal Ion Golgi To Plasma Membrane Transport Trans-Golgi Network Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Transport Vesicle Liver Development Transforming Growth Factor Beta Receptor Signaling Pathway FAR/SIN/STRIPAK Complex Protein Phosphatase Type 2A Complex Response To Lead Ion Negative Regulation Of DNA Repair Vacuolar Transport Negative Regulation Of Double-strand Break Repair Vesicle-mediated Transport To The Plasma Membrane Response To Calcium Ion Host-mediated Activation Of Viral Process Phosphoprotein Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Negative Regulation Of Nerve Growth Factor Production Dibasic Protein Processing Zymogen Inhibition Transmembrane Transporter Binding Cellular Response To Fluid Shear Stress Metanephric Cortical Collecting Duct Development Response To Fluid Shear Stress Metanephric Cortex Development Metanephric Distal Tubule Development RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Golgi To Plasma Membrane Protein Transport Homocarnosine Synthase Activity Carnosine Synthase Activity Carnosine Biosynthetic Process Kinesin I Complex Tau Protein Binding Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Chloride:proton Antiporter Activity Lysosome Positive Regulation Of Protein Catabolic Process Protein Targeting To Vacuole Rab GDP-dissociation Inhibitor Activity Leading Edge Cell Differentiation Golgi Apparatus Subcompartment Regulation Of Nerve Growth Factor Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Peptidase Activity Nerve Growth Factor Production Negative Regulation Of Neurotrophin Production Polycystin Complex Metanephric Smooth Muscle Tissue Development
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