PSMG2 and PSMG1

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PSMG2	PSMG1
Description		proteasome assembly chaperone 2	proteasome assembly chaperone 1
Image
GO Annotations	Cellular Component	Nucleus Cytosol Protein Folding Chaperone Complex	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Protein Folding Chaperone Complex
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Apoptotic Process Proteasome Assembly Chaperone-mediated Protein Complex Assembly Regulation Of Cell Cycle	Cerebellar Granule Cell Precursor Proliferation Proteasome Assembly Chaperone-mediated Protein Complex Assembly Proteasome Core Complex Assembly
Pathways		Proteasome assembly Proteasome assembly	Proteasome assembly Proteasome assembly
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Pulse pressure ( 30224653 30578418)	Alanine aminotransferase levels ( 33547301) Ankylosing spondylitis ( 20062062) C-reactive protein levels ( 21300955) Daytime nap ( 33568662) Daytime sleep phenotypes ( 27126917) Eye morphology ( 29921221) Fibrinogen ( 23969696) Fibrinogen levels ( 26561523 28107422) Finger osteoarthritis severity (hand Klsum) ( 33055079) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Inflammatory bowel disease ( 18758464) Pediatric autoimmune diseases ( 26301688) Primary sclerosing cholangitis ( 27992413 23603763) Serum alkaline phosphatase levels ( 33547301) Takayasu arteritis ( 23830517) Triglyceride levels ( 32203549) Ulcerative colitis ( 20228799)
Interacting Genes		5 interacting genes: KRT31 NOTCH2NLA PSMG1 SLC35F6 TCF4	10 interacting genes: BRCA1 CEBPA CSDE1 PRKAR1A PRKAR1B PSMG2 SNRNP70 SPTAN1 UBE2A YME1L1
Entrez ID		56984	8624
HPRD ID		11638	05598
Ensembl ID		ENSG00000128789	ENSG00000183527
Uniprot IDs		Q969U7 Q9P1R6	O95456
PDB IDs		8QYJ 8QYL 8QYM 8QYN 8QYS 8QZ9 8TM3 8TM4 8TM5 8TM6 8YIX 8YIY 8YIZ	8QYJ 8QYL 8QYM 8QYN 8QYS 8QZ9 8TM3 8TM4 8TM5 8TM6 8YIX 8YIY 8YIZ
Enriched GO Terms of Interacting Partners?		Proteasome Core Complex Assembly	CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Cellular Response To Tumor Necrosis Factor Protein Kinase A Catalytic Subunit Binding Response To Tumor Necrosis Factor CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Postreplication Repair Cellular Response To Cytokine Stimulus Ubiquitin Conjugating Enzyme Activity Regulation Of CAMP/PKA Signal Transduction Multivesicular Body Ciliary Base RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Iduronate-2-sulfatase Activity
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