PSG11 and SHD

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		PSG11	SHD
Description		pregnancy specific beta-1-glycoprotein 11	Src homology 2 domain containing transforming protein D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Surface
	Molecular Function	Protein Binding	Phosphotyrosine Residue Binding Protein Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Female Pregnancy
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Post-bronchodilator lung function in asthma (FVC) ( 32989782)
Interacting Genes		3 interacting genes: NLGN3 RBPMS SHD	14 interacting genes: ABL1 BECN1 CAPN10 EGFR ERBB2 ERBB3 ERBB4 KRTCAP2 MET MRPS22 NCK2 OLIG1 OSBPL6 PSG11
Entrez ID		5680	56961
HPRD ID		08898	15337
Ensembl ID		ENSG00000243130	ENSG00000105251
Uniprot IDs		Q9UQ72	Q96IW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Proteasome Regulatory Particle, Lid Subcomplex Proteasome Regulatory Particle Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Cell Adhesion Mediator Activity Signaling Receptor Activity Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell Adhesion Molecule Binding Pre-mRNA Intronic Binding MRNA CDS Binding Asymmetric, Glutamatergic, Excitatory Synapse Regulation Of Respiratory Gaseous Exchange By Nervous System Process Inhibitory Postsynaptic Potential Positive Regulation Of Glutamate Receptor Signaling Pathway Rhythmic Synaptic Transmission Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Regulation Of Glutamate Receptor Signaling Pathway Symmetric, GABA-ergic, Inhibitory Synapse Neuron To Neuron Synapse Presynaptic Membrane Organization Neurexin Family Protein Binding Presynapse Assembly Regulation Of Respiratory System Process Neuron Cell-cell Adhesion Proteasome Accessory Complex Positive Regulation Of Immune Response To Tumor Cell Pre-mRNA Binding Presynapse Organization	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Protein Tyrosine Kinase Activity Basal Plasma Membrane ERBB2 Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Neuron Differentiation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Programmed Cell Death Receptor Complex ERBB3:ERBB2 Complex Protein Kinase Activity Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Cellular Response To Growth Factor Stimulus Negative Regulation Of Programmed Cell Death Response To Growth Factor Regulation Of Apoptotic Process Kinase Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB2-EGFR Signaling Pathway Glial Cell Development Positive Regulation Of Cell Communication Positive Regulation Of MAPK Cascade Positive Regulation Of Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Negative Regulation Of Apoptotic Process Basolateral Plasma Membrane Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cell Population Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Animal Organ Development Regulation Of Intracellular Signal Transduction Regulation Of ERK1 And ERK2 Cascade Endosome Membrane Protein Tyrosine Kinase Activator Activity Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Glial Cell Differentiation Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Signal Transduction
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