MEPCE and TRAPPC14

		MEPCE	TRAPPC14
Description		methylphosphate capping enzyme	trafficking protein particle complex subunit 14
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus 7SK SnRNP Ribonucleoprotein Complex	Cytoplasm Spindle Cytoskeleton Plasma Membrane Midbody Vesicle Centriolar Satellite Mitotic Spindle TRAPPII Protein Complex
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity O-methyltransferase Activity RNA Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Transferase Activity SnRNA Binding 7SK SnRNA Binding RNA 5'-gamma-phosphate Methyltransferase Activity	Protein Binding Alpha-tubulin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RNA Methylation SnRNA Metabolic Process Methylation SnRNA Modification Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II	Cell Projection Organization Regulation Of Cell Population Proliferation Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: ERBB2 RN7SK	8 interacting genes: AGXT CYSRT1 KRTAP6-1 NBPF19 NOTCH2NLA TGM1 TMEM50A VWC2
Entrez ID		56257	55262
HPRD ID		07889	07716
Ensembl ID		ENSG00000146834	ENSG00000146826
Uniprot IDs		Q7L2J0	B3KNS5 Q8WVR3
PDB IDs		5UNA 6DCB 6DCC 7SLP 7SLQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding Positive Regulation Of Cell Growth ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Demethylase Activity DNA N6-methyladenine Demethylase Activity Midbody Broad Specificity Oxidative DNA Demethylase Activity Cleavage Furrow Ingression Protein Demethylase Activity Membrane Invagination Engulfment Of Target By Autophagosome 7SK SnRNP	Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-serine-pyruvate Transaminase Activity Oxalic Acid Secretion Cornified Envelope Positive Regulation Of Cell Cycle Keratinization Cell Envelope Organization Set3 Complex Positive Regulation Of Cell Cycle G1/S Phase Transition Rpd3L-Expanded Complex Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle RNA 5'-gamma-phosphate Methyltransferase Activity Glycine Biosynthetic Process Notch Signaling Pathway Glyoxylate Catabolic Process L-alanine Catabolic Process Alanine-glyoxylate Transaminase Activity L-alanine Metabolic Process L-cysteine Catabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP SnRNA Modification Protein-glutamine Gamma-glutamyltransferase Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle O-methyltransferase Activity Interstitial Matrix Oxalate Transport Glyoxylate Metabolic Process Extrinsic Component Of Postsynaptic Membrane Regulation Of Cell Cycle G1/S Phase Transition 7SK SnRNA Binding Positive Regulation Of Protein Localization To Cajal Body Sulfur Amino Acid Catabolic Process Cysteine Metabolic Process Serine Family Amino Acid Catabolic Process SnRNA Binding
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