MEPCE

Description		methylphosphate capping enzyme
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GO Annotations	Cellular Component	Nucleus 7SK SnRNP Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity O-methyltransferase Activity RNA Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Transferase Activity SnRNA Binding 7SK SnRNA Binding RNA 5'-gamma-phosphate Methyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RNA Methylation SnRNA Metabolic Process Methylation SnRNA Modification Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		4 novel interacting genes: ALKBH4 NFE4 SMURF1 TRAPPC14
Interacting Genes		2 interacting genes: ERBB2 RN7SK
Entrez ID		56257
HPRD ID		07889
Ensembl ID		ENSG00000146834
Uniprot IDs		Q7L2J0
PDB IDs		5UNA 6DCB 6DCC 7SLP 7SLQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding Positive Regulation Of Cell Growth ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Demethylase Activity DNA N6-methyladenine Demethylase Activity Midbody Broad Specificity Oxidative DNA Demethylase Activity Cleavage Furrow Ingression Protein Demethylase Activity Membrane Invagination Engulfment Of Target By Autophagosome 7SK SnRNP
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