EAPP and AAR2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		EAPP	AAR2
Description		E2F associated phosphoprotein	AAR2 splicing factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Spliceosomal Complex U5 SnRNP
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Transcription Elongation By RNA Polymerase II	Spliceosomal Tri-snRNP Complex Assembly MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 23936387) Insulin-related traits (multivariate analysis) ( 32002517) Metabolite levels ( 23823483)	Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		5 interacting genes: AAR2 BYSL TNFAIP8 UBE3A UBQLN4	2 interacting genes: EAPP GJA5
Entrez ID		55837	25980
HPRD ID		12631	12767
Ensembl ID		ENSG00000129518	ENSG00000131043
Uniprot IDs		Q56P03	Q9Y312
PDB IDs			7PJH
Enriched GO Terms of Interacting Partners?		Tolerance Induction To Lipopolysaccharide Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Sperm Entry Positive Regulation Of Golgi Lumen Acidification Negative Regulation Of Chronic Inflammatory Response Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of CD40 Signaling Pathway Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Protein Ubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Osteoclast Proliferation Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Protein K48-linked Ubiquitination Regulation Of CD40 Signaling Pathway B-1 B Cell Homeostasis Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Cellular PH Reduction Regulation Of Golgi Lumen Acidification Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Cytosolic Proteasome Complex Regulation Of Germinal Center Formation Regulation Of Post-translational Protein Modification Intracellular Receptor Signaling Pathway Preribosome, Small Subunit Precursor Regulation Of Protein Localization To Nucleolus Protein Polyubiquitination Regulation Of Toll-like Receptor 3 Signaling Pathway Protein K11-linked Deubiquitination Regulation Of Chronic Inflammatory Response Positive Regulation Of Hepatocyte Proliferation Ubiquitin-protein Transferase Activity Progesterone Receptor Signaling Pathway Prostate Gland Growth K48-linked Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Vascular Wound Healing Negative Regulation Of Bone Resorption Regulation Of Hepatocyte Proliferation Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Autophagosome Maturation Proteolysis Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Negative Regulation Of Bone Remodeling K63-linked Deubiquitinase Activity Trophectodermal Cell Differentiation Tolerance Induction	Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Heart Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential DGTPase Activity DGTP Binding Triphosphoric Monoester Hydrolase Activity Deoxynucleoside Triphosphate Hydrolase Activity Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication DATP Catabolic Process DGTP Catabolic Process Blood Vessel Morphogenesis Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Renin Secretion Into Blood Stream Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Regulation Of AV Node Cell Action Potential Male Germ Cell Proliferation DGTP Metabolic Process Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Eukaryotic Translation Initiation Factor 2 Complex DATP Metabolic Process Purine Deoxyribonucleoside Triphosphate Catabolic Process Gap Junction Hemi-channel Activity Connexin Binding Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Deoxyribonucleoside Triphosphate Catabolic Process Animal Organ Development SA Node Cell Action Potential Atrioventricular Valve Development AV Node Cell To Bundle Of His Cell Communication Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
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