POLR3B and CKAP4

		POLR3B	CKAP4
Description		RNA polymerase III subunit B	cytoskeleton associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytoplasm Cytosol Nuclear DNA-directed RNA Polymerase Complex	Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytoskeleton Plasma Membrane Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	DNA Binding DNA-directed RNA Polymerase Activity Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity Ribonucleoside Binding 5'-3' RNA Polymerase Activity Metal Ion Binding DNA/RNA Hybrid Binding	RNA Binding Protein Binding
	Biological Process	Immune System Process DNA-templated Transcription Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production SnRNA Transcription By RNA Polymerase III Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation RND3 GTPase cycle RND2 GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive test performance ( 17903297) Glioblastoma ( 26424050) Glioma ( 26424050) Morning person ( 30696823) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Tourette syndrome ( 22889924)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: DSCAM	15 interacting genes: ASCC2 ATF4 DKK1 HAMP LINC01554 MLH1 MVP NDUFB7 NEIL3 NKX3-1 OGT PLAT THOC7 TSNAX WASHC3
Entrez ID		55703	10970
HPRD ID		11447	16717
Ensembl ID		ENSG00000013503	ENSG00000136026
Uniprot IDs		Q9NW08	Q07065
PDB IDs		7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Positive Regulation Of Axon Extension Involved In Axon Guidance Lamellar Body Netrin-activated Signaling Pathway Regulation Of Axon Extension Involved In Axon Guidance Dendrite Self-avoidance Camera-type Eye Photoreceptor Cell Differentiation Dendritic Spine Development Eye Photoreceptor Cell Differentiation Photoreceptor Cell Differentiation Retina Layer Formation Cell-cell Adhesion Mediator Activity Positive Regulation Of Axon Extension Rough Endoplasmic Reticulum Dendrite Morphogenesis Social Behavior Synaptic Transmission, Glutamatergic Neuron Recognition Protein Tyrosine Kinase Binding Azurophil Granule Membrane
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