MSTO1 and HDDC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSTO1	HDDC3
Description		misato mitochondrial distribution and morphology regulator 1	HD domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Mitochondrion Organization Positive Regulation Of Mitochondrial Fusion Mitochondrion Distribution
Pathways
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Serum cancer antigen 15.3 levels ( 31666285) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		7 interacting genes: CASP9 EP300 HDDC3 NR1H3 OGT RUNX1 UBE3A	14 interacting genes: AKAP9 APP CCDC172 CCHCR1 CEP57L1 CFTR EXOC5 GKAP1 GOLGA8EP GOLGA8F MAGEA4 MSTO1 NMI TPM3
Entrez ID		55154	374659
HPRD ID		16904	14635
Ensembl ID		ENSG00000125459	ENSG00000184508
Uniprot IDs		A0A3B3IUD2 Q9BUK6	Q8N4P3
PDB IDs			3NR1 5VXA
Enriched GO Terms of Interacting Partners?		Response To Hormone Positive Regulation Of TORC1 Signaling Chromatin DNA Binding Positive Regulation Of TOR Signaling Regulation Of TORC1 Signaling Regulation Of Proteolysis Regulation Of TOR Signaling Platelet Formation Histone Acetyltransferase Complex Hemopoiesis Response To Ketone Response To Steroid Hormone Positive Regulation Of Transcription By RNA Polymerase II Response To Progesterone Protein Maturation Caspase Complex Cellular Response To Oxygen-containing Compound Myeloid Cell Differentiation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Transcription Coactivator Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of Protein Metabolic Process Peptidyl-lysine Propionylation Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Regulation Of Small Molecule Metabolic Process Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Regulation Of Protein Localization Cellular Response To Nutrient Levels Histone Crotonyltransferase Activity Regulation Of Gluconeogenesis Rhythmic Process TORC1 Signaling Sperm Entry Positive Regulation Of Golgi Lumen Acidification Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Secretion Of Lysosomal Enzymes Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Developmental Growth Positive Regulation Of Alpha-beta T Cell Activation	Cellular Response To CAMP Response To CAMP
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