HEATR3 and GPT2

		HEATR3	GPT2
Description		HEAT repeat containing 3	glutamic--pyruvic transaminase 2
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Unfolded Protein Binding	L-alanine:2-oxoglutarate Aminotransferase Activity Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding
	Biological Process	Protein Import Into Nucleus Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Erythrocyte Maturation	2-oxoglutarate Metabolic Process L-alanine Metabolic Process L-alanine Catabolic Process
Pathways
Drugs			Pyridoxal phosphate Glutamic acid Alanine Phenelzine
Diseases
GWAS		Appendicular lean mass ( 33097823) Epilepsy ( 30531953) Esophageal cancer (squamous cell) ( 22960999) Glioblastoma ( 28346443) Glioma ( 28346443) Mean reticulocyte volume ( 32888494) Red cell distribution width ( 28957414) Systemic lupus erythematosus ( 33272962) Testicular germ cell tumor ( 23666239 23666240 28604728 28604732) Uterine fibroids ( 31249589)
Interacting Genes		2 interacting genes: AKT1 CEBPA	3 interacting genes: AKT1 APP OGT
Entrez ID		55027	84706
HPRD ID		07945	06307
Ensembl ID		ENSG00000155393	ENSG00000166123
Uniprot IDs		Q7Z4Q2	Q8TD30
PDB IDs			3IHJ
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Fat Cell Differentiation Integrated Stress Response Signaling Kinase Binding Response To Tumor Necrosis Factor Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Fat Cell Differentiation Regulation Of TRNA Methylation Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Carbohydrate Homeostasis Positive Regulation Of Protein Localization To Endoplasmic Reticulum Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process Response To Insulin-like Growth Factor Stimulus Mammalian Oogenesis Stage Regulation Of Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Mitochondrion Organization Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Positive Regulation Of Protein Catabolic Process TRNA (guanine-N7)-methylation Response To Ketone TORC2 Complex Binding Cellular Response To Rapamycin Small Molecule Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of Protein Localization To Lysosome Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Endodeoxyribonuclease Activity Cellular Response To Metal Ion SREBP-SCAP Complex Retention In Endoplasmic Reticulum CHOP-C/EBP Complex Response To Vitamin B2 White Fat Cell Proliferation C/EBP Complex L-alanine Metabolic Process L-alanine Catabolic Process L-alanine:2-oxoglutarate Aminotransferase Activity Negative Regulation Of SREBP Signaling Pathway Negative Regulation Of Fatty Acid Beta-oxidation Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex	Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Proteolysis Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Synapse Organization Response To Nerve Growth Factor Negative Regulation Of Translational Initiation Phosphatidylinositol-3,4,5-trisphosphate Binding Regulation Of Proteolysis Regulation Of Small Molecule Metabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Translational Initiation Positive Regulation Of Nitric Oxide Metabolic Process Cellular Response To Nerve Growth Factor Stimulus Regulation Of Translation Regulation Of Glycolytic Process Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of TORC1 Signaling Regulation Of Nitric Oxide Metabolic Process TORC1 Signaling Regulation Of Carbohydrate Catabolic Process Regulation Of Lymphocyte Migration Negative Regulation Of Protein Ubiquitination Regulation Of ATP Metabolic Process Protein Localization To Organelle Regulation Of Phosphorus Metabolic Process TOR Signaling Regulation Of TORC1 Signaling Regulation Of Glucose Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation Negative Regulation Of Post-translational Protein Modification Positive Regulation Of TOR Signaling Positive Regulation Of Lipid Biosynthetic Process Regulation Of TRNA Methylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Import Into Nucleus Cytoplasmic Translation Import Into Nucleus Positive Regulation Of Mitotic Cell Cycle Protein-containing Complex Positive Regulation Of Protein Localization To Endoplasmic Reticulum
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?