DNAAF5 and INTS1

		DNAAF5	INTS1
Description		dynein axonemal assembly factor 5	integrator complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Microtubule Cytoskeleton Motile Cilium Mitotic Spindle Dynein Axonemal Particle	Nucleus Nucleoplasm Membrane Nuclear Membrane Integrator Complex INTAC Complex
	Molecular Function	Dynein Intermediate Chain Binding	Protein Binding
	Biological Process	Cilium Movement Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly	Blastocyst Growth Inner Cell Mass Cell Proliferation Embryo Implantation SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II U2 SnRNA 3'-end Processing Negative Regulation Of Apoptotic Process RNA Polymerase II Transcription Initiation Surveillance
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Initial pursuit acceleration ( 29064472) Retinitis pigmentosa ( 33514863)	Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812)
Interacting Genes		5 interacting genes: FEZ1 PFKL USP39 WEE2-AS1 ZBTB16	4 interacting genes: CTDP1 DEAF1 MTNR1B RNF10
Entrez ID		54919	26173
HPRD ID		07903	10899
Ensembl ID		ENSG00000164818	ENSG00000164880
Uniprot IDs		B3KPE2 Q86Y56	Q8N201
PDB IDs			7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?			Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Nervous System Process Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of System Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep TFIIF-class Transcription Factor Complex Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Negative Regulation Of Schwann Cell Proliferation
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