ANKRD49 and FKBPL

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)

		ANKRD49	FKBPL
Description		ankyrin repeat domain 49	FKBP prolyl isomerase like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Spermatogenesis Cell Differentiation Positive Regulation Of DNA-templated Transcription	Response To Radiation Regulation Of Angiogenesis Regulation Of Blood Vessel Branching
Pathways			The role of GTSE1 in G2/M progression after G2 checkpoint
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Hand grip strength ( 29691431) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: CFTR ENKD1 FKBPL PKNOX1 SMARCD1	4 interacting genes: ANKRD49 APP CALCOCO2 UNC119
Entrez ID		54851	63943
HPRD ID		16893	16901
Ensembl ID		ENSG00000168876	ENSG00000204315
Uniprot IDs		Q8WVL7	A0A024RCQ6 Q9UIM3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Caveolin-mediated Endocytosis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Metabolic Process Axon Choice Point Recognition Regulation Of Caveolin-mediated Endocytosis Xenophagy Positive Regulation Of Autophagosome Maturation Positive Regulation Of Phosphate Metabolic Process Peptidase Activator Activity Response To Light Stimulus Chemical Synaptic Transmission Cellular Response To Manganese Ion Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Endocytosis Positive Regulation Of Protein Tyrosine Kinase Activity Trans-synaptic Signaling Synaptic Signaling
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