NSMCE4A and ATE1

		NSMCE4A	ATE1
Description		NSE4A component of SMC5/6 complex	arginyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Chromosome Nuclear Body Smc5-Smc6 Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Arginyl-tRNA--protein Transferase Activity Protein Binding Transferase Activity Acyltransferase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Protein Sumoylation Regulation Of Telomere Maintenance Chromatin Looping	Ubiquitin-dependent Protein Catabolic Process Response To Oxidative Stress Proteasomal Protein Catabolic Process Protein Arginylation Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein Targeting To Vacuole Involved In Autophagy Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways		SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS			Chronotype ( 30696823)
Interacting Genes		5 interacting genes: HSPB1 OGT SRPK1 SRPK2 TRIM31	2 interacting genes: NTAN1 SUV39H1
Entrez ID		54780	11101
HPRD ID		16585	06979
Ensembl ID		ENSG00000107672	ENSG00000107669
Uniprot IDs		Q9NXX6	A0A8I5KTH0 A0A8I5KZ24 B3KWA3 B4DK25 B4E107 F5GXE4 F8WAC9 O95260
PDB IDs			8TZV 8UAU
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Process Regulation Of Viral Process Response To Stress Protein Modification Process Positive Regulation Of Viral Genome Replication Transferase Activity Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Response To Other Organism Negative Regulation Of Protein Kinase C Signaling Regulation Of Viral Genome Replication Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein K63-linked Ubiquitination Arginyl-tRNA--protein Transferase Activity Protein-containing Complex Assembly Response To External Biotic Stimulus Protein Localization To Vacuole Defense Response Regulation Of Translational Initiation Regulation Of Viral Life Cycle Protein-containing Complex Organization Regulation Of MRNA Splicing, Via Spliceosome Protein Arginylation Protein Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Protein-containing Complex Assembly Innate Immune Response Protein Kinase C Inhibitor Activity Protein O-acetylglucosaminyltransferase Activity Nuclear Speck Organization Intracellular Signal Transduction Defense Response To Symbiont Regulation Of Protein Kinase C Signaling Regulation Of RNA Splicing Defense Response To Other Organism Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Protein-RNA Complex Assembly Chromatin Organization Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Magnesium Ion Binding Carbon Catabolite Regulation Of Transcription Anterograde Axonal Protein Transport R-loop Processing Regulation Of Transcription By Glucose NSL Complex
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