MPHOSPH8 and MTRNR2L1

Number of citations of the paper that reports this interaction (PubMedID 16583711)
0

Data Source:
BioGRID (two hybrid)

		MPHOSPH8	MTRNR2L1
Description		M-phase phosphoprotein 8	MT-RNR2 like 1 (pseudogene)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleosome Heterochromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Plasma Membrane	Extracellular Region Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding Histone H3K9me2/3 Reader Activity	Receptor Antagonist Activity
	Biological Process	Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Gene Expression, Epigenetic Constitutive Heterochromatin Formation Transposable Element Silencing By Heterochromatin Formation	Negative Regulation Of Execution Phase Of Apoptosis
Pathways		Negative Regulation of CDH1 Gene Transcription Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Drugs
Diseases
GWAS		Colorectal cancer ( 34062886)
Interacting Genes		5 interacting genes: H3C1 MTRNR2L1 RANBP9 SH3BP4 SIRT1	8 interacting genes: EEF1A1 HSP90AA1 MPHOSPH8 PPA1 PRDX1 PSMA5 TSFM USP40
Entrez ID		54737	100462977
HPRD ID		13682
Ensembl ID		ENSG00000196199
Uniprot IDs		Q99549
PDB IDs		3LWE 3QO2 3R93 3SVM 6V2S 7M5U 8QFB
Enriched GO Terms of Interacting Partners?		Negative Regulation Of TOR Signaling NAD-dependent Protein Decrotonylase Activity Histone H4K12 Deacetylase Activity, Hydrolytic Mechanism Negative Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Maintenance Of Nucleus Location Histone Decrotonylase Activity, NAD-dependent Histone H3K14 Deacetylase Activity, NAD-dependent Negative Regulation Of Cellular Response To Testosterone Stimulus Histone H3K Deacetylase Activity NAD-dependent Protein Lysine Delactylase Activity Regulation Of Cellular Response To Testosterone Stimulus Behavioral Response To Starvation Negative Regulation Of Peptidyl-lysine Acetylation Histone H4K16 Deacetylase Activity, NAD-dependent Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Negative Regulation Of Prostaglandin Biosynthetic Process Protein Depropionylation Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Macrophage Apoptotic Process ENoSc Complex Regulation Of TOR Signaling Positive Regulation Of CAMP-dependent Protein Kinase Activity Amino Acid Import Negative Regulation Of Protein Acetylation Positive Regulation Of Autophagy Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Mobilization Pyrimidine Dimer Repair By Nucleotide-excision Repair HLH Domain Binding Histone Deacetylase Activity, NAD-dependent Regulation Of CAMP-dependent Protein Kinase Activity RDNA Heterochromatin Keratin Filament Binding RDNA Heterochromatin Formation Regulation Of Endodeoxyribonuclease Activity Stress-induced Premature Senescence NAD-dependent Protein Lysine Deacetylase Activity Epigenetic Regulation Of Gene Expression Small GTPase Binding Ovulation From Ovarian Follicle Regulation Of Bile Acid Biosynthetic Process Pyrimidine Dimer Repair Regulation Of Transcription By Glucose Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Single Strand Break Repair Subtelomeric Heterochromatin Formation Chromatin Silencing Complex Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore UV-damage Excision Repair	Ficolin-1-rich Granule Lumen Secretory Granule Lumen Translation Elongation Factor Activity Translational Elongation CTP Binding DATP Binding Extracellular Exosome Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Melanosome
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