PNLIPRP2 and CLPS

Number of citations of the paper that reports this interaction (PubMedID 15287741)
0

Data Source:
HPRD (in vitro)

		PNLIPRP2	CLPS
Description		pancreatic lipase related protein 2 (gene/pseudogene)	colipase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Cytoplasmic Vesicle Zymogen Granule Membrane Cell Projection Neuron Projection	Extracellular Region
	Molecular Function	Lipoprotein Lipase Activity Phospholipase Activity Triacylglycerol Lipase Activity Calcium Ion Binding Protein Binding Phospholipase A1 Activity Lipase Activity Hydrolase Activity Metal Ion Binding Monoacylglycerol Lipase Activity Galactolipase Activity Carboxylic Ester Hydrolase Activity	Enzyme Activator Activity Lipase Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process Triglyceride Metabolic Process Phospholipid Catabolic Process Lipid Catabolic Process Galactolipid Catabolic Process Triglyceride Catabolic Process High-density Lipoprotein Particle Remodeling Phosphatidylcholine Catabolic Process Cholesterol Homeostasis Lipid Digestion	Retinoid Metabolic Process Lipid Metabolic Process Digestion Response To Bacterium Lipid Catabolic Process Response To Food
Pathways		Digestion of dietary lipid Developmental Lineage of Pancreatic Acinar Cells	Digestion of dietary lipid Retinoid metabolism and transport
Drugs		Capric dimethyl amine oxide	B-nonylglucoside (Hydroxyethyloxy)Tri(Ethyloxy)Octane METHOXYUNDECYLPHOSPHINIC ACID
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369) Low density lipoprotein cholesterol levels ( 32154731) Phospholipid levels (plasma) ( 22359512)	Blood protein levels ( 30072576)
Interacting Genes		1 interacting genes: CLPS	4 interacting genes: GLP1R LIPF PNLIP PNLIPRP2
Entrez ID		5408	1208
HPRD ID		05110	00356
Ensembl ID		ENSG00000266200	ENSG00000137392
Uniprot IDs		A0AAG2UV77 P54317	A0A087WZW1 A0A087X0Q7 P04118
PDB IDs		2OXE 2PVS
Enriched GO Terms of Interacting Partners?		Lipase Binding Mitogen-activated Protein Kinase Kinase Binding JUN Kinase Kinase Kinase Activity Positive Regulation Of JUN Kinase Activity Mitogen-activated Protein Kinase Kinase Kinase Binding MAP Kinase Kinase Kinase Activity Digestion Response To Food	Triacylglycerol Lipase Activity Lipase Activity Carboxylic Ester Hydrolase Activity Triglyceride Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Lipoprotein Lipase Activity Triglyceride Catabolic Process Phospholipase A1 Activity High-density Lipoprotein Particle Remodeling Acylglycerol Catabolic Process Lipid Catabolic Process Glycerolipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Sterol Homeostasis Cholesterol Homeostasis Glucagon-like Peptide 1 Receptor Activity Positive Regulation Of Triglyceride Lipase Activity Galactolipase Activity Fatty Acid Biosynthetic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Galactolipid Catabolic Process Lipid Homeostasis Glucagon Receptor Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Malate Dehydrogenase Activity Lipid Metabolic Process Lipid Digestion Response To Psychosocial Stress Carboxylic Acid Biosynthetic Process Retinyl-palmitate Esterase Activity Post-translational Protein Targeting To Membrane, Translocation Fatty Acid Metabolic Process Positive Regulation Of Lipase Activity Malate Metabolic Process Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Intestinal Cholesterol Absorption Cellular Response To Glucagon Stimulus Monoacylglycerol Lipase Activity Phosphatidylcholine Catabolic Process Activation Of Adenylate Cyclase Activity Intestinal Lipid Absorption Hydrolase Activity Small Molecule Biosynthetic Process Zymogen Granule Membrane Positive Regulation Of Adenylate Cyclase Activity Monocarboxylic Acid Metabolic Process
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