PCP4 and CALML6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PCP4	CALML6
Description		Purkinje cell protein 4	calmodulin like 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Nucleus Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Calmodulin Binding	Calcium Ion Binding Protein Binding Enzyme Regulator Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Neuron Differentiation Positive Regulation Of CAMKK-AMPK Signaling Cascade	Microtubule Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Metabolite levels ( 23823483) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 12 weeks) ( 28437668)	Body mass index ( 26426971)
Interacting Genes		7 interacting genes: CALM1 CALML6 DAPK1 PAX6 POT1 TERF1 TERF2IP	2 interacting genes: MAP3K7 PCP4
Entrez ID		5121	163688
HPRD ID		03378	12997
Ensembl ID		ENSG00000183036	ENSG00000169885
Uniprot IDs		P48539	B1AKR1 Q8TD86
PDB IDs		2N77
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Telomeric D-loop Disassembly Negative Regulation Of Chromosome Organization Telomeric Loop Disassembly DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromosome, Telomeric Region Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomerase DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Negative Regulation Of Endodeoxyribonuclease Activity Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Negative Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Regulation Of Chromosome Organization Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of DNA Metabolic Process Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Type II Interferon Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Negative Regulation Of Deoxyribonuclease Activity Cytotoxic T Cell Pyroptotic Cell Death Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Telomeric Loop Disassembly	Regulation Of CAMKK-AMPK Signaling Cascade Positive Regulation Of CAMKK-AMPK Signaling Cascade I-kappaB Phosphorylation Interleukin-17A-mediated Signaling Pathway Linear Polyubiquitin Binding MAP Kinase Kinase Kinase Kinase Activity Histone Kinase Activity TRNA Pseudouridine Synthase Activity TRNA Pseudouridine Synthesis MyD88-dependent Toll-like Receptor Signaling Pathway ATAC Complex P38MAPK Cascade Positive Regulation Of Cell Size Type II Transforming Growth Factor Beta Receptor Binding Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of JUN Kinase Activity MAP Kinase Activity Anoikis Positive Regulation Of CGAS/STING Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Stress-activated MAPK Cascade Interleukin-33-mediated Signaling Pathway Protein Serine/threonine Kinase Binding Response To Angiotensin Toll-like Receptor 3 Signaling Pathway Cellular Response To Lectin Cellular Response To Angiotensin MAP Kinase Kinase Kinase Activity Fc-epsilon Receptor Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Pseudouridine Synthesis Pseudouridine Synthase Activity Endolysosomal Toll-like Receptor Signaling Pathway Interleukin-1-mediated Signaling Pathway CGAS/STING Signaling Pathway Positive Regulation Of T Cell Cytokine Production Protein Exit From Endoplasmic Reticulum Non-canonical NF-kappaB Signal Transduction
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