PRLH and PRLHR

Number of citations of the paper that reports this interaction (PubMedID 11030716)
17

Data Source:
HPRD (in vivo, in vitro)

		PRLH	PRLHR
Description		prolactin releasing hormone	prolactin releasing hormone receptor
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm	Plasma Membrane Cilium Membrane Neuron Projection
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Prolactin-releasing Peptide Receptor Binding	G Protein-coupled Receptor Activity Neuropeptide Y Receptor Activity Protein Binding Neuropeptide Receptor Activity Neuropeptide Binding
	Biological Process	Tissue Homeostasis Response To Dietary Excess Reduction Of Food Intake In Response To Dietary Excess Energy Reserve Metabolic Process Lipid Metabolic Process G Protein-coupled Receptor Signaling Pathway Feeding Behavior Response To Glucose Response To Insulin Regulation Of Multicellular Organism Growth Eating Behavior Response To Peptide Hormone Fat Cell Differentiation Autonomic Nervous System Development	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Feeding Behavior Hormone Metabolic Process
Pathways		Peptide ligand-binding receptors	Peptide ligand-binding receptors
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Height ( 28552196) Leisure-time exercise behaviour (age-stratified) ( 30102679) Pancreatic cancer ( 22158540) Triglyceride levels ( 32203549)
Interacting Genes		1 interacting genes: PRLHR	3 interacting genes: PICK1 PRLH SNTA1
Entrez ID		51052	2834
HPRD ID		04046	02937
Ensembl ID		ENSG00000071677	ENSG00000119973
Uniprot IDs		P81277 Q53QV7	A5JUU5 P49683
PDB IDs		8ZPS 8ZPT 9K26 9K27	8ZPS 8ZPT 9K26 9K27
Enriched GO Terms of Interacting Partners?		Neuropeptide Binding Neuropeptide Receptor Activity Neuropeptide Y Receptor Activity Neuropeptide Signaling Pathway Feeding Behavior Female Pregnancy Hormone Metabolic Process	Actin Binding Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ventricular Cardiac Muscle Cell Action Potential Nitric-oxide Synthase Binding Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Response To Nutrient Levels Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Neuronal Ion Channel Clustering Arp2/3 Complex Binding Dendritic Spine Maintenance Long-term Synaptic Depression Reduction Of Food Intake In Response To Dietary Excess Autonomic Nervous System Development Prolactin-releasing Peptide Receptor Binding Response To Dietary Excess Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Sodium Channel Regulator Activity Regulation Of Membrane Repolarization Positive Regulation Of Receptor Internalization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Dendritic Spine Organization Negative Regulation Of Synaptic Transmission Regulation Of Actin Nucleation Neuropeptide Hormone Activity Eating Behavior Cardiac Muscle Cell Action Potential
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