AMDHD2 and GNPDA2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AMDHD2	GNPDA2
Gene Name		amidohydrolase domain containing 2	glucosamine-6-phosphate deaminase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	N-acetylglucosamine-6-phosphate Deacetylase Activity Metal Ion Binding	Glucosamine-6-phosphate Deaminase Activity Hydrolase Activity
	Biological Process	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process N-acetylneuraminate Catabolic Process	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process
Pathways
Drugs
Diseases
GWAS			Body mass index ( 23563607 19079261 23669352 20935630 23583978) Obesity ( 23563607)
Protein-Protein Interactions		2 interactors: GNPDA2 TRIP13	2 interactors: AMDHD2 TRIM27
Entrez ID		51005	132789
HPRD ID		13034	13594
Ensembl ID		ENSG00000162066	ENSG00000163281
Uniprot IDs		Q9Y303	Q8TDQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Female Meiosis I Synaptonemal Complex Assembly N-acetylglucosamine Metabolic Process Synaptonemal Complex Organization Oocyte Maturation Male Meiosis I Female Meiotic Division Reciprocal Meiotic Recombination Oocyte Development Oocyte Differentiation Amino Sugar Metabolic Process Synapsis Homologous Chromosome Segregation Male Meiosis Oogenesis Meiotic Chromosome Segregation Meiosis I Female Gamete Generation Spermatid Development Cell Maturation Spermatid Differentiation Double-strand Break Repair	Negative Regulation Of Interleukin-2 Secretion N-acetylneuraminate Catabolic Process Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion N-acetylneuraminate Metabolic Process Negative Regulation Of Viral Release From Host Cell Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import N-acetylglucosamine Metabolic Process Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Calcium Ion Transport Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Ion Transmembrane Transport Amino Sugar Metabolic Process Negative Regulation Of Transmembrane Transport Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Viral Transcription Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Viral Process
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