NAP1L3 and GLA

		NAP1L3	GLA
Description		nucleosome assembly protein 1 like 3	galactosidase alpha
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Cytoplasm Lysosome Golgi Apparatus Membrane Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Catalytic Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Alpha-galactosidase Activity Signaling Receptor Binding Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Protein Homodimerization Activity
	Biological Process	Nucleosome Assembly	Carbohydrate Metabolic Process Lipid Metabolic Process Oligosaccharide Metabolic Process Glycoside Catabolic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Glycosylceramide Catabolic Process Glycosphingolipid Catabolic Process Negative Regulation Of Nitric-oxide Synthase Activity
Pathways			Neutrophil degranulation Glycosphingolipid catabolism
Drugs			Migalastat
Diseases			Fabry disease
GWAS		Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: BEND7 TSPYL4 USP25	3 interacting genes: OGT TERT UBC
Entrez ID		4675	2717
HPRD ID		02123	02357
Ensembl ID		ENSG00000186310	ENSG00000102393
Uniprot IDs		Q8IYV1 Q99457	A0A3B3IUC4 A0A6Q8PHD1 P06280 Q53Y83
PDB IDs			1R46 1R47 3GXN 3GXP 3GXT 3HG2 3HG3 3HG4 3HG5 3LX9 3LXA 3LXB 3LXC 3S5Y 3S5Z 3TV8 4NXS 6IBK 6IBM 6IBR 6IBT 8K7D 8K7E 8K7F 8K7G 8K7H 8K7I 8K7J 8K7K 8K7L 9AVS
Enriched GO Terms of Interacting Partners?		Glycosylceramide Catabolic Process Negative Regulation Of Nitric-oxide Synthase Activity Regulation Of Nitric-oxide Synthase Activity Glycoside Catabolic Process Alpha-galactosidase Activity Negative Regulation Of Interleukin-17-mediated Signaling Pathway Ubiquitin-like Protein Peptidase Activity Interleukin-17A-mediated Signaling Pathway Negative Regulation Of ERAD Pathway Negative Regulation Of Oxidoreductase Activity Negative Regulation Of Response To Oxidative Stress SUMO Binding Glycosylceramide Metabolic Process Glycosphingolipid Catabolic Process Ceramide Catabolic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Oxidoreductase Activity Glycolipid Catabolic Process Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein K63-linked Deubiquitination Regulation Of ERAD Pathway Deubiquitinase Activity Protein K48-linked Deubiquitination Regulation Of Response To Oxidative Stress Sphingolipid Catabolic Process
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