- and GGCT

Data Source: HiPPIP (Novel)

		-	GGCT
Name		TCR gamma alternate reading frame protein	gamma-glutamylcyclotransferase
Structure		No pdb structure
GO Annotations	Cellular Component	None	Cytosol Extracellular Exosome
	Molecular Function	None	Gamma-glutamylcyclotransferase Activity Lyase Activity Protein Homodimerization Activity
	Biological Process	None	Release Of Cytochrome C From Mitochondria
Pathways		None	Glutathione synthesis and recycling
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535 )	No GWAS studies recorded
Novel Interactors		4 novel interactors: CPVL GGCT IL6 TBX20	2 novel interactors: - DNAH11
Interacting Genes		1 interacting genes: APP	1 interacting genes: APP
Entrez ID		445347	79017
HPRD ID		15468	12912
Ensembl ID		ENSG00000289746	ENSG00000006625
Uniprot IDs		Q0VGM3	A0A090N7V5 O75223
PDB IDs		Not available	2I5T 2PN7 2Q53 2RBH 3CRY
GO Terms Enriched among Interactors		Amyloid-beta Complex Positive Regulation Of Interleukin-1 Production Growth Cone Lamellipodium Positive Regulation Of Apoptotic Process Positive Regulation Of Chemokine Production Positive Regulation Of Programmed Cell Death Regulation Of Chemokine Production Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-6 Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Interleukin-1 Beta Production Defense Response To Gram-negative Bacterium Regulation Of Interleukin-1 Beta Production Glucagon Secretion Neutrophil Apoptotic Process Positive Regulation Of Epithelial To Mesenchymal Transition Lateral Mesoderm Formation Embryonic Heart Tube Elongation Tricuspid Valve Development Acetylcholine Receptor Activator Activity Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Defense Response To Gram-positive Bacterium Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Interleukin-21 Production Regulation Of Epithelial To Mesenchymal Transition Hepatic Immune Response Foramen Ovale Closure Pulmonary Valve Formation Pulmonary Vein Morphogenesis PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cell Activation Involved In Immune Response Positive Regulation Of Chemotaxis Endosome To Plasma Membrane Transport Vesicle Regulation Of Interleukin-6 Production Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Primary MiRNA Processing	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Learning Or Memory Axon Midline Choice Point Recognition Microtubule-based Transport Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Determination Of Left/right Asymmetry In Nervous System Proximal Portion Of Axoneme Protein Localization To Motile Cilium 9+0 Motile Cilium Regulation Of Spontaneous Synaptic Transmission Cognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Microtubule-based Movement Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding