CCDC196 and KRT28

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC196	KRT28
Description		coiled-coil domain containing 196	keratin 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function		Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process		Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Cirrhosis (alcohol related) ( 32853455)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Glucose homeostasis traits ( 25524916)
Interacting Genes		32 interacting genes: AMOTL2 ANKRD11 BORCS5 DTNB EIF3F HGS IFT74 KRT20 KRT28 KRT31 KRT34 KRT35 KRT37 KRT39 MEIS2 MEOX2 NXF1 PIK3R3 PKNOX2 RAB3IP SKA1 SNAPC5 STX11 SYCE1L SYCE2 TFIP11 TXLNA TXLNB UBL5 USHBP1 WASF1 ZGPAT	23 interacting genes: ABI3 CCDC196 DEUP1 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT76 KRT79 KRT8 KRT80 KRT81 KRT86 NUP58 UCHL5 USHBP1 WASHC1
Entrez ID		440184	162605
HPRD ID		14708	17245
Ensembl ID		ENSG00000196553	ENSG00000173908
Uniprot IDs		A0A1B0GTZ2 A0A1B0GV15 A0A286YEX8	Q7Z3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Organelle Organization Morphogenesis Of An Epithelium Supramolecular Fiber Organization Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Anatomical Structure Morphogenesis Cytoskeleton Synaptonemal Complex Assembly Synaptonemal Complex Organization	Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Extracellular Exosome Cytosol Structural Constituent Of Cytoskeleton Epidermis Development Peptide Cross-linking Intermediate Filament Polymerization
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