MOV10 and ADORA3

		MOV10	ADORA3
Description		Mov10 RNA helicase	adenosine A3 receptor
Image		No pdb structure
GO Annotations	Cellular Component	P-body Extracellular Space Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule P Granule	Plasma Membrane Membrane Dendrite Presynaptic Membrane Synapse Schaffer Collateral - CA1 Synapse
	Molecular Function	Nucleotide Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity 5'-3' RNA Helicase Activity	G Protein-coupled Adenosine Receptor Activity G Protein-coupled Receptor Activity
	Biological Process	Transposable Element Silencing Regulatory NcRNA-mediated Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Defense Response To Virus Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Transposable Element Silencing By MRNA Destabilization Regulation Of Neuron Projection Arborization	G Protein-coupled Adenosine Receptor Signaling Pathway Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Regulation Of Heart Contraction Negative Regulation Of Cell Population Proliferation Response To Wounding Regulation Of Norepinephrine Secretion Negative Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways		Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux Nuclear events stimulated by ALK signaling in cancer Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH1 mRNA translation by microRNAs Regulation of NPAS4 mRNA translation Regulation of MITF-M-dependent genes involved in apoptosis TGFBR3 expression Regulation of PD-L1(CD274) translation	Adenosine P1 receptors G alpha (i) signalling events
Drugs			Caffeine Adenosine Enprofylline Aminophylline Piclidenoson Fostamatinib
Diseases
GWAS		Blood pressure ( 21909110) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 30487518 28739976 27618452 25249183 21909115) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Hip circumference adjusted for BMI ( 25673412) Hypertension ( 21909115 30487518 25249183) Mean arterial pressure ( 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (diuretics) ( 31015401) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 28739976 27841878 27618452 25249183 21909115 30487518) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Energy intake ( 30071075) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: RNF10 YTHDF1
Entrez ID		4343	140
HPRD ID		14732	08984
Ensembl ID		ENSG00000155363	ENSG00000282608
Uniprot IDs		Q5JR04 Q9HCE1	A0A0J9YWR0 H6VQ59 P0DMS8
PDB IDs			8X16 8X17
Enriched GO Terms of Interacting Partners?			Transposable Element Silencing By MRNA Destabilization 5'-3' RNA Helicase Activity 3'-UTR-mediated MRNA Destabilization Regulation Of Neuron Projection Arborization P Granule Transposable Element Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of MRNA Catabolic Process Post-transcriptional Gene Silencing MRNA Destabilization MiRNA-mediated Post-transcriptional Gene Silencing RNA Helicase Activity Helicase Activity RNA Destabilization P-body Cytoplasmic Ribonucleoprotein Granule Cytoplasmic Stress Granule Positive Regulation Of MRNA Metabolic Process Regulatory NcRNA-mediated Gene Silencing Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Cell Morphogenesis
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