MOV10

Gene Name		Mov10 RISC complex RNA helicase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Extracellular Space Cytosol
	Molecular Function	Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Epidermal Growth Factor Receptor Signaling Pathway Notch Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway MRNA Cleavage Involved In Gene Silencing By MiRNA Fc-epsilon Receptor Signaling Pathway Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling
Pathways		Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease PIP3 activates AKT signaling Cellular Senescence Signaling by Wnt Signaling by EGFRvIII in Cancer Oncogene Induced Senescence Signaling by SCF-KIT Downstream signaling events of B Cell Receptor (BCR) DAP12 signaling PI3K/AKT activation PI-3K cascade Pre-NOTCH Transcription and Translation PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Pre-NOTCH Expression and Processing Innate Immune System Signaling by PDGF Signalling by NGF DAP12 interactions GAB1 signalosome Signaling by NOTCH Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by ERBB4 Signaling by Overexpressed Wild-Type EGFR in Cancer Role of LAT2/NTAL/LAB on calcium mobilization PI3K events in ERBB4 signaling Signaling by FGFR beta-catenin independent WNT signaling Signaling by ERBB2 Signaling by EGFR Ca2+ pathway Oxidative Stress Induced Senescence Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Diastolic blood pressure ( 21909115) Hypertension ( 21909115) Systolic blood pressure ( 21909115)
Protein-protein Interactions		1 interactors: EIF2AK2
Entrez ID		4343
HPRD ID		14732
Ensembl ID		ENSG00000155363
Uniprot IDs		Q5JR04 Q9H8T8 Q9HCE1
PDB IDs
Enriched GO Terms of Interacting Partners?		Evasion Or Tolerance By Virus Of Host Immune Response Regulation Of Hematopoietic Stem Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation Regulation Of Hematopoietic Stem Cell Proliferation Response To Host Immune Response Regulation Of NLRP3 Inflammasome Complex Assembly Regulation Of Translational Initiation In Response To Stress Negative Regulation Of Osteoblast Proliferation Modulation By Virus Of Host Process Regulation Of Translation In Response To Stress Response To Interferon-alpha Modulation By Virus Of Host Morphology Or Physiology Regulation Of Osteoblast Proliferation Regulation Of Defense Response To Virus By Virus Negative Regulation Of Defense Response To Virus Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Chemokine Production Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Regulation Of Chemokine Production Activation Of MAPKK Activity Regulation Of Viral Genome Replication Regulation Of Translational Initiation Negative Regulation Of Viral Process Regulation Of Defense Response To Virus Negative Regulation Of Translation Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Interaction With Host ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Regulation Of Stem Cell Proliferation Positive Regulation Of NF-kappaB Transcription Factor Activity Response To Unfolded Protein Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Viral Process Defense Response To Virus Response To Endoplasmic Reticulum Stress Regulation Of Stress-activated MAPK Cascade Viral Life Cycle Protein Autophosphorylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Virus Activation Of Protein Kinase Activity Regulation Of Translation Peptidyl-tyrosine Phosphorylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		accompanied associates dissociation h3k27me3 hairpin helicase ink4a interacts locus lys27 mostly noncoding pcg polycomb prc1 precise prompting purifies putative reassessment repression repressive rna settings shrna silencing transcriptional trimethylation upregulation