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MOV10
Description
Mov10 RNA helicase
Image
No pdb structure
GO Annotations
Cellular Component
P-body
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Cytoplasmic Ribonucleoprotein Granule
P Granule
Molecular Function
Nucleotide Binding
RNA Binding
RNA Helicase Activity
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
5'-3' RNA Helicase Activity
Biological Process
Transposable Element Silencing
Regulatory NcRNA-mediated Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
MiRNA-mediated Post-transcriptional Gene Silencing
MiRNA-mediated Gene Silencing By MRNA Destabilization
Defense Response To Virus
Positive Regulation Of MRNA Catabolic Process
3'-UTR-mediated MRNA Destabilization
Transposable Element Silencing By MRNA Destabilization
Regulation Of Neuron Projection Arborization
Pathways
Pre-NOTCH Transcription and Translation
Oxidative Stress Induced Senescence
Oncogene Induced Senescence
Ca2+ pathway
TP53 Regulates Metabolic Genes
MAPK6/MAPK4 signaling
Transcriptional Regulation by VENTX
Regulation of RUNX1 Expression and Activity
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Regulation of PTEN mRNA translation
Competing endogenous RNAs (ceRNAs) regulate PTEN translation
Transcriptional Regulation by MECP2
Transcriptional Regulation by MECP2
Estrogen-dependent gene expression
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Nuclear events stimulated by ALK signaling in cancer
Regulation of CDH11 mRNA translation by microRNAs
Regulation of CDH11 mRNA translation by microRNAs
Regulation of CDH1 mRNA translation by microRNAs
Regulation of NPAS4 mRNA translation
Regulation of MITF-M-dependent genes involved in apoptosis
TGFBR3 expression
Regulation of PD-L1(CD274) translation
Drugs
Diseases
GWAS
Blood pressure (
21909110
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Body size at age 10 (
32376654
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (
32963231
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical surface area (visual PC2) (
32198502
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Diastolic blood pressure (
27841878
30487518
28739976
27618452
25249183
21909115
)
Diastolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Glaucoma (primary open-angle) (
33627673
)
Height (
31562340
)
Hip circumference adjusted for BMI (
25673412
)
Hypertension (
21909115
30487518
25249183
)
Mean arterial pressure (
30487518
)
Mean arterial pressure x alcohol consumption interaction (2df test) (
29912962
)
Medication use (diuretics) (
31015401
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Systolic blood pressure (
28739976
27841878
27618452
25249183
21909115
30487518
)
Systolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Novel Interacting Genes
3 novel interacting genes:
ADORA3
ATP5PB
TSPAN2
Interacting Genes
2 interacting genes:
RNF10
YTHDF1
Entrez ID
4343
HPRD ID
14732
Ensembl ID
ENSG00000155363
Uniprot IDs
Q5JR04
Q9HCE1
PDB IDs
Enriched GO Terms of Interacting Partners
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