ART3 and ALCAM

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ART3	ALCAM
Gene Name		ADP-ribosyltransferase 3	activated leukocyte cell adhesion molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome	Focal Adhesion External Side Of Plasma Membrane Integral Component Of Membrane Axon Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function	NAD+ ADP-ribosyltransferase Activity NAD(P)+-protein-arginine ADP-ribosyltransferase Activity	Receptor Binding Protein Binding
	Biological Process	Protein ADP-ribosylation	Cell Adhesion Signal Transduction Axon Guidance Motor Neuron Axon Guidance
Pathways			Axon guidance L1CAM interactions
Drugs
Diseases
GWAS			Erectile dysfunction ( 22704111)
Protein-Protein Interactions		2 interactors: ALCAM PRKCD	3 interactors: ART3 CD6 EGFR
Entrez ID		419	214
HPRD ID		04363	03389
Ensembl ID		ENSG00000156219	ENSG00000170017
Uniprot IDs		Q13508	B3KNN9 Q13740 Q6PEY4
PDB IDs			1KJC
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Interleukin-10 Production Negative Regulation Of Filopodium Assembly Interleukin-12 Production Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Superoxide Anion Generation Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Positive Regulation Of Protein Dephosphorylation Neutrophil Activation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Lipid Catabolic Process Regulation Of Platelet Activation Cellular Senescence Motor Neuron Axon Guidance Negative Regulation Of Insulin Receptor Signaling Pathway B Cell Proliferation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Activation Of Phospholipase C Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Protein Binding Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Regulation Of Lipid Catabolic Process Negative Regulation Of Coagulation Positive Regulation Of Lipid Transport Positive Regulation Of Lipid Biosynthetic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Wound Healing Positive Regulation Of Response To DNA Damage Stimulus Termination Of Signal Transduction Response To External Stimulus Cell Aging Negative Regulation Of Actin Filament Polymerization Execution Phase Of Apoptosis Positive Regulation Of Phospholipase Activity Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of MAP Kinase Activity	Alkanesulfonate Metabolic Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Activation Of Phospholipase A2 Activity Positive Regulation Of Phospholipase A2 Activity Response To Cobalamin Response To UV-A Response To Hydroxyisoflavone Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Catenin Import Into Nucleus Regulation Of Phospholipase A2 Activity Regulation Of Superoxide Anion Generation Magnesium Ion Homeostasis Cellular Response To Estradiol Stimulus Protein Insertion Into Membrane Astrocyte Development Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Catenin Import Into Nucleus Protein ADP-ribosylation Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Cellular Response To Estrogen Stimulus Cellular Response To Dexamethasone Stimulus Positive Regulation Of Vasoconstriction Positive Regulation Of Vasodilation
Tagcloud ?			1a3 2a12 blindness cadaveric cd166 cobblestone contaminating corneal corneas cultivated enrichment frozen grafts hcenc hcsf hpsc hybridomas mabs mixtures monolayer noteworthy obstacle peroxiredoxin pluripotent prdx quantitatively restore tag vision
Tagcloud (Difference) ?			1a3 2a12 blindness cadaveric cd166 cobblestone contaminating corneal corneas cultivated enrichment frozen grafts hcenc hcsf hpsc hybridomas mabs mixtures monolayer noteworthy obstacle peroxiredoxin pluripotent prdx quantitatively restore tag vision
Tagcloud (Intersection) ?