ERVFRD-1 and NXPE3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERVFRD-1	NXPE3
Description		endogenous retrovirus group FRD member 1, envelope	neurexophilin and PC-esterase domain family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Myoblast Fusion
Pathways
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: APP BCL2L2 CCL4L2 ERMP1 FXR1 GPHB5 MIP NINJ2 NXPE3 PAEP SEC22A SLC30A8 SLC41A2 TAP1 TMPRSS4	6 interacting genes: APP CYB5R3 ERVFRD-1 FAM209A GOLM2 MRM1
Entrez ID		405754	91775
HPRD ID		13648	10073
Ensembl ID		ENSG00000244476	ENSG00000144815
Uniprot IDs		P60508	A0A994J739 Q969Y0
PDB IDs		1Y4M 6RX3 7OIX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Long-term Synaptic Potentiation Monoatomic Cation Transmembrane Transporter Activity	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Nitric-oxide Synthase Complex RRNA (guanine) Methyltransferase Activity RRNA 2'-O-methylation RRNA (guanosine-2'-O-)-methyltransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Nitrite Reductase (NO-forming) Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion
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