PSMG4 and PSMG3

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (pull down, affinity chromatography technology)

		PSMG4	PSMG3
Description		proteasome assembly chaperone 4	proteasome assembly chaperone 3
Image
GO Annotations	Cellular Component	Cytosol Protein-containing Complex	Cytosol Protein-containing Complex
	Molecular Function	Protein-containing Complex Binding	Protein Binding Protein-containing Complex Binding Molecular Adaptor Activity
	Biological Process	Proteasome Assembly	Proteasome Assembly Chaperone-mediated Protein Complex Assembly
Pathways		Proteasome assembly Proteasome assembly	Proteasome assembly Proteasome assembly
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 32888494)	Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812) Femur bone mineral density x serum urate levels interaction ( 34046847) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		1 interacting genes: PSMG3	6 interacting genes: PSMB1 PSMB3 PSMB4 PSMB5 PSMG4 TAP2
Entrez ID		389362	84262
HPRD ID		19577	14404
Ensembl ID		ENSG00000180822	ENSG00000157778
Uniprot IDs		D6RB92 Q5JS54	Q9BT73
PDB IDs		5WTQ 8QYJ 8TM3	2Z5E 6JPT 8QYJ 8TM3
Enriched GO Terms of Interacting Partners?		Proteasome Assembly Chaperone-mediated Protein Complex Assembly	Proteasome Core Complex, Beta-subunit Complex Proteasome Core Complex Proteasome Complex Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteasome Assembly Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Proteolysis Tapasin Binding Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Via ER Pathway, TAP-dependent ABC-type Peptide Antigen Transporter Activity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-dependent Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Peptide Transmembrane Transporter Activity TAP Complex Peptide Antigen Transport ABC-type Peptide Transporter Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib TAP1 Binding Cytosol To Endoplasmic Reticulum Transport Catabolic Process MHC Class Ib Protein Binding Extracellular Exosome MHC Protein Binding MHC Class I Peptide Loading Complex Threonine-type Endopeptidase Activity Peptide Antigen Assembly With MHC Class I Protein Complex Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Protein-containing Complex Assembly T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Protein-containing Complex Organization Protein Metabolic Process Antigen Processing And Presentation Of Endogenous Antigen Negative Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I T Cell Mediated Immunity Peptide Antigen Binding Lipopolysaccharide Binding Cytosol Antigen Processing And Presentation Of Exogenous Peptide Antigen ABC-type Transporter Activity Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Exogenous Antigen
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