TSPYL6 and ERLEC1

		TSPYL6	ERLEC1
Description		TSPY like 6	endoplasmic reticulum lectin 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Nucleosome Assembly	Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: DVL3 KANK2 KRTAP13-2 KRTAP19-5 KRTAP19-6 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGEA6 MDFI RBPMS	1 interacting genes: STK11
Entrez ID		388951	27248
HPRD ID		11652	10310
Ensembl ID		ENSG00000178021	ENSG00000068912
Uniprot IDs		A0A140VJY4 Q8N831	Q96DZ1 V9HWD3
PDB IDs			8KES 8KET 8KEV
Enriched GO Terms of Interacting Partners?		Intermediate Filament
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