KRTAP5-3 and LCE3C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP5-3	LCE3C
Description		keratin associated protein 5-3	late cornified envelope 3C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Epidermis Development Keratinization Killing Of Cells Of Another Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Keratinization	Formation of the cornified envelope
Drugs		Beta-D-Glucose
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		64 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CREB5 CRY2 CYSRT1 ECM1 FBXO34 FUCA2 GLRX3 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP15-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-1 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RAMP3 RGS17 RGS20 SMCP	66 interacting genes: ADAMTSL4 ALPP CHIC2 CYP21A2 CYSRT1 EFEMP2 GRN HOXA1 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1F LCE2B LCE2D LCE4A LCE5A MDFI NBPF19 NOTCH2NLA NUFIP2 PCSK5 PLSCR1 RGS17 RGS20 SPRY1 SPRY2 TRIM42 TSPAN4 VASN ZNF655
Entrez ID		387266	353144
HPRD ID		12395	17262
Ensembl ID		ENSG00000196224	ENSG00000244057
Uniprot IDs		Q6L8H2	Q5T5A8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Identical Protein Binding Protein Binding	Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Cytosol Tissue Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Bud Elongation Involved In Lung Branching Regulation Of Lens Fiber Cell Differentiation Protein Binding Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Neurotrophin TRK Receptor Signaling Pathway
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