KCNJ9 and KCNJ3

Number of citations of the paper that reports this interaction (PubMedID 12297500)
0

Data Source:
HPRD (in vivo, in vitro)

		KCNJ9	KCNJ3
Description		potassium inwardly rectifying channel subfamily J member 9	potassium inwardly rectifying channel subfamily J member 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex Presynaptic Membrane Parallel Fiber To Purkinje Cell Synapse Inward Rectifier Potassium Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex External Side Of Plasma Membrane Cell Surface Membrane T-tubule Monoatomic Ion Channel Complex Presynaptic Membrane Parallel Fiber To Purkinje Cell Synapse Inward Rectifier Potassium Channel Complex I(KACh) Inward Rectifier Potassium Channel Complex
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity Ligand-gated Monoatomic Cation Channel Activity	Inward Rectifier Potassium Channel Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding G-protein Activated Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Potassium Ion Import Across Plasma Membrane	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Response To Electrical Stimulus Potassium Ion Transmembrane Transport Regulation Of Heart Rate By Cardiac Conduction Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Regulation Of Presynaptic Membrane Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Ethanol Isavuconazole	Atomoxetine Ethanol Halothane B-nonylglucoside Dronedarone Ifenprodil
Diseases
GWAS		Alcohol consumption over the past year ( 29058377)	Age at voice drop ( 27182965) Alcoholic chronic pancreatitis ( 28754779) Automobile speeding propensity ( 30643258) Dentures ( 31235808) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Feeling miserable ( 29500382) General cognitive ability ( 29844566) Leisure-time exercise behaviour ( 30102679) Leisure-time exercise behaviour (age-stratified) ( 30102679) Lung function (FEV1/FVC) ( 30061609) Metabolite levels ( 23823483) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Risk-taking tendency (4-domain principal component model) ( 30643258) Rosacea symptom severity ( 29771307) Smoking initiation ( 33082346 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 24871463)
Interacting Genes		6 interacting genes: ADRB2 DRD2 DRD4 KCNJ3 KCNJ6 TMEM201	5 interacting genes: CRK GNB1 KCNJ5 KCNJ6 KCNJ9
Entrez ID		3765	3760
HPRD ID		02959	03323
Ensembl ID		ENSG00000162728	ENSG00000162989
Uniprot IDs		Q92806	D2X9V0 D2XBF0 P48549
PDB IDs		6X23
Enriched GO Terms of Interacting Partners?		Potassium Channel Regulator Activity Norepinephrine Binding Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission G-protein Activated Inward Rectifier Potassium Channel Activity Dopamine Neurotransmitter Receptor Activity Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Dopamine Binding Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission Phospholipase C-activating Dopamine Receptor Signaling Pathway Behavioral Response To Ethanol Response To Histamine Regulation Of Monoatomic Ion Transport Regulation Of Membrane Potential Synaptic Transmission, Dopaminergic Behavioral Response To Cocaine Regulation Of Neurotransmitter Uptake Arachidonate Secretion G Protein-coupled Dopamine Receptor Signaling Pathway Inward Rectifier Potassium Channel Activity Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Response To Amphetamine Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Inorganic Ion Transmembrane Transport Temperature Homeostasis Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Regulation Of Transport Potassium Ion Import Across Plasma Membrane Response To Amine Negative Regulation Of Blood Pressure Long-chain Fatty Acid Transport Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Smooth Muscle Contraction Monoatomic Ion Transport Regulation Of Multicellular Organism Growth G Protein-coupled Receptor Activity Regulation Of Sodium Ion Transport Negative Regulation Of Protein Secretion Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Receptor Internalization Intracellular Monoatomic Cation Homeostasis Regulation Of Amine Transport Voltage-gated Potassium Channel Complex Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis	G-protein Activated Inward Rectifier Potassium Channel Activity Inward Rectifier Potassium Channel Activity Potassium Ion Import Across Plasma Membrane Inward Rectifier Potassium Channel Complex Voltage-gated Potassium Channel Complex Inorganic Cation Import Across Plasma Membrane Monoatomic Ion Channel Complex Import Across Plasma Membrane Potassium Ion Transmembrane Transport Potassium Ion Transport Signaling Receptor Complex Adaptor Activity Regulation Of Monoatomic Ion Transmembrane Transport Glycerol-3-phosphate Dehydrogenase (quinone) Activity Regulation Of Monoatomic Ion Transport Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Glycerol-3-phosphate Shuttle I(KACh) Inward Rectifier Potassium Channel Complex DN4 Thymocyte Differentiation Cerebellar Neuron Development Ligand-gated Monoatomic Cation Channel Activity Metal Ion Transport Glycerol Catabolic Process Glycerol-3-phosphate Metabolic Process Monoatomic Cation Transmembrane Transport Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Inorganic Cation Transmembrane Transport Import Into Cell Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Diapedesis Positive Regulation Of Artery Morphogenesis Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Artery Morphogenesis Positive Regulation Of Receptor Clustering Cellular Response To Insulin-like Growth Factor Stimulus Reelin-mediated Signaling Pathway Response To Endothelin Cellular Response To Endothelin Postsynaptic Specialization Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Monoatomic Ion Transport Positive Thymic T Cell Selection Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Ventricular Cardiac Muscle Cell Membrane Repolarization
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